Outcomes of Patients Living with HIV Hospitalized due to COVID-19: A 3-Year Nationwide Study (2020–2022).
Scientific reports on the association between human immunodeficiency virus (HIV) in patients with COVID-19 and mortality have not been in agreement. In this nationwide study, we described and analyzed the demographic and clinical characteristics of people living with HIV (PLWH) and established that...
| Publicado en: | AIDS & Behavior Vol. 28; no. 9; pp. 3093 - 3103 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Sep2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179574209&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179574209 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Sep2024 vid: 28 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 179574209 178265716 179574209 179574209 10.1007/s10461-024-04394-z 179574209 ppf: 3093 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Outcomes of Patients Living with HIV Hospitalized due to COVID-19: A 3-Year Nationwide Study (2020–2022). aug: au: Garcia-Carretero, Rafael Vazquez-Gomez, Oscar Rodriguez-Maya, Belen Gil-Prieto, Ruth Gil-de-Miguel, Angel affil: https://ror.org/01v5cv687 Department of Internal Medicine, Mostoles University Hospital, Rey Juan Carlos University (Madrid), Madrid, Spain sug: subj: HIV-Positive Persons COVID-19 Comorbidity Hospitalization Outcomes (Health Care) HIV Infections Complications Mortality Risk Factors Risk Assessment Human Funding Source Inpatients Comparative Studies Logistic Regression Multivariate Analysis Bivariate Statistics Machine Learning Algorithms Odds Ratio Confidence Intervals Adult Middle Age Aged Male Female Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Scientific reports on the association between human immunodeficiency virus (HIV) in patients with COVID-19 and mortality have not been in agreement. In this nationwide study, we described and analyzed the demographic and clinical characteristics of people living with HIV (PLWH) and established that HIV infection is a risk factor for mortality in patients hospitalized due to COVID-19. We collected data from the National Hospital Data Information System at Hospitalization between 2020 and 2022. We included patients admitted to the hospital with a diagnosis of COVID-19. We established a cohort of patients with PLWH and compared them to patients without HIV (non-PLWH). For multivariate analyses, we performed binary logistic regression, using mortality as the dependent variable. To improve the interpretability of the results we also applied penalized regression and random forest, two well-known machine-learning algorithms. A broad range of comorbidities, as well as sex and age data, were included in the final model as adjusted estimators. Our data of 1,188,160 patients included 6,973 PLWH. The estimated hospitalization rate in this set was between 1.43% and 1.70%, while the rate among the general population was 0.83%. Among patients with COVID-19, HIV infection was a risk factor for mortality with an odds ratio (OR) of 1.25 (95% CI, 1.14–1.37, p < 0.001). PLWH are more likely to be hospitalized due to COVID-19 than are non-PLWH. PLWH are 25% more likely to die due to COVID-19 than non-PLWH. Our results highlight that PLWH should be considered a population at risk for both hospitalization and mortality. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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