Differential online and offline effects of theta-tACS on memory encoding and retrieval.
Theta oscillations support memory formation, but their exact contribution to the communication between prefrontal cortex (PFC) and the hippocampus is unknown. We tested the functional relevance of theta oscillations as a communication link between both areas for memory formation using transcranial a...
| Publicado en: | Cognitive, Affective & Behavioral Neuroscience Vol. 24; no. 5; pp. 894 - 912 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179574522&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179574522 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15307026 NA4 jtl: Cognitive, Affective & Behavioral Neuroscience issn: 15307026 maglogo: N pubinfo: dt: Oct2024 vid: 24 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 179574522 178730186 10.3758/s13415-024-01204-w 179574522 ppf: 894 ppct: 18 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Differential online and offline effects of theta-tACS on memory encoding and retrieval. aug: au: Paßmann, Sven Baselgia, Sandrine Kasten, Florian H. Herrmann, Christoph S. Rasch, Björn affil: https://ror.org/022fs9h90 Cognitive Biopsychology and Methods, Department of Psychology, Université Fribourg, Rue P.-A.-de-Faucigny 2, 1700, Fribourg, Switzerland sug: ab: Theta oscillations support memory formation, but their exact contribution to the communication between prefrontal cortex (PFC) and the hippocampus is unknown. We tested the functional relevance of theta oscillations as a communication link between both areas for memory formation using transcranial alternating current stimulation (tACS). Healthy, young participants learned two lists of Dutch-German word pairs and retrieved them immediately and with a 30-min delay. In the encoding group (N = 30), tACS was applied during the encoding of list 1. List 2 was used to test stimulation aftereffects. In the retrieval group (N = 23), we stimulated during the delayed recall. In both groups, we applied tACS bilaterally at prefrontal and tempo-parietal sites, using either individualized theta frequency or 15 Hz (as control), according to a within-subject design. Stimulation with theta-tACS did not alter overall learning performance. An exploratory analysis revealed that immediate recall improved when word-pairs were learned after theta-tACS (list 2). Applying theta-tACS during retrieval had detrimental effects on memory. No changes in the power of the respective frequency bands were observed. Our results do not support the notion that impacting the communication between PFC and the hippocampus during a task by bilateral tACS improves memory. However, we do find evidence that direct stimulation had a trend for negatively interfering effects during immediate and delayed recall. Hints for beneficial effects on memory only occurred with aftereffects of the stimulation. Future studies need to further examine the effects during and after stimulation on memory formation. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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