| Sumario: | Purpose: Depression experienced during marriage affects the dynamics of marriage and life. This study aimed to examine the mediating effect of depression on the relationship between marital satisfaction and quality of life in women. Methods: The data were collected by the researchers using a Participant Information Form, the Marriage Satisfaction Scale, the Beck Depression Scale, and the World Health Organization Quality of Life Scale - Short Form. In the evaluation of the data, analyses were made by establishing a Structural Equation Model with the AMOS 24 package program. Results: There was a statistically significant negative correlation between the dependent variable of depression and the independent variable of marital satisfaction (β1=-0.636; p=.001 < .05). There was a statistically significant negative correlation between the dependent variable of quality of life and the independent variable of depression (β1=0.250; p=.001 < .05). There was a statistically significant positive correlation between the independent variable of marital satisfaction and the independent variable of quality of life (β1=0.620; p=.001 < .05). Conclusions: According to the results of the mediation effect analysis based on the bootstrap method, it was found that the depression score has a mediator effect between marital satisfaction and quality of life.
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