Efficacy of Oral Gabapentin and Acetaminophen for Postoperative Analgesia in Anorectal Surgery: A Fuzzy Logic Evaluation.
Background: The present study attempted to evaluate the effect of oral gabapentin and acetaminophen for postoperative analgesia in anorectal surgery. Methods: This double-blind clinical trial was carried out on 144 patients who were candidates for anorectal surgery. The patients were randomly assign...
| Publicado en: | Middle East Journal of Digestive Diseases Vol. 16; no. 2; pp. 114 - 119 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Iranian Association of Gastroenterology & Hepatology
Apr2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179603583&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179603583 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20085230 BG4K jtl: Middle East Journal of Digestive Diseases issn: 20085230 maglogo: N pubinfo: dt: Apr2024 vid: 16 iid: 2 pid: 70725 pub: Iranian Association of Gastroenterology & Hepatology artinfo: ui: 179603583 179603583 179603583 10.34172/mejdd.2024.378 179603583 ppf: 114 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Efficacy of Oral Gabapentin and Acetaminophen for Postoperative Analgesia in Anorectal Surgery: A Fuzzy Logic Evaluation. aug: au: Hosseini, Seyed Jalal Ishagh Barjoei, Pouya Derakhshan Bahadorzadeh, Mojdeh Seifaddini, Amin Vahedian, Mostafa affil: Department of General Surgery, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran sug: subj: Anus Diseases Surgery Rectal Diseases Surgery Preoperative Care Postoperative Pain Drug Therapy Analgesics Therapeutic Use Gabapentin Administration and Dosage Acetaminophen Administration and Dosage Pain Management Evaluation Treatment Outcomes Human Randomized Controlled Trials Random Assignment Funding Source Placebos Descriptive Statistics Data Analysis, Statistical Visual Analog Scaling Decision Support Systems, Clinical Models, Theoretical ab: Background: The present study attempted to evaluate the effect of oral gabapentin and acetaminophen for postoperative analgesia in anorectal surgery. Methods: This double-blind clinical trial was carried out on 144 patients who were candidates for anorectal surgery. The patients were randomly assigned into three groups of control, acetaminophen 500 mg, and gabapentin 300 mg for two hours before the surgery. Data on pain severity based on the visual analog scale (VAS) were evaluated and analyzed. Results: The results of the current study indicated that in patients taking acetaminophen and gabapentin tablets before surgery, the amount of postoperative pain decreased, and the amount of decrease in postoperative pain in the patients who received acetaminophen and gabapentin tablets compared with the placebo group was significant (P < 0.001). Also, an evaluation was done using a proposed fuzzy logic model. Conclusion: Taking acetaminophen and gabapentin tablets one hour before the operation causes a significant reduction in postoperative pain in patients who are candidates for anorectal surgery. The results are promising and encourage one to pay attention to more studies with the goal of possibly using them as a decision-support model in the future. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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