Development of Postsurgical Pyoderma Gangrenosum with New Keloid after Keloid Resection.
Keloids are a dermal fibroproliferative disorder and can arise from trauma, acne, vaccination, and herpes zoster. Pyoderma gangrenosum (PG) is a painful ulcerative skin disorder that is associated with neutrophilic dysfunction. However, the pathophysiologies of keloids and PG are not fully understoo...
| Published in: | Advances in Skin & Wound Care Vol. 37; no. 9; pp. 499 - 503 |
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| Main Authors: | , , , , |
| Format: | case study pictorial tables/charts Journal Article |
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Lippincott Williams & Wilkins
Sep2024
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179658305&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179658305 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15277941 38T jtl: Advances in Skin & Wound Care issn: 15277941 maglogo: N pubinfo: dt: Sep2024 vid: 37 iid: 9 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 179658305 179658305 179658305 10.1097/ASW.0000000000000197 179658305 ppf: 499 ppct: 4 formats: tig: atl: Development of Postsurgical Pyoderma Gangrenosum with New Keloid after Keloid Resection. aug: au: Yusaku Saijo Hiroaki Kuwahara Keigo Ito Rei Ogawa Satoshi Akaishi affil: Plastic Surgeon, Department of Plastic and Reconstructive Surgery, Nippon Medical School Hospital, Tokyo sug: subj: Pyoderma Gangrenosum Surgery Postoperative Complications Pyoderma Keloid Surgery Recurrence Wound Care Female Adult Keloid Physiopathology Adalimumab Therapeutic Use Adrenal Cortex Hormones Administration and Dosage Taping and Strapping Wound Healing Biopsy Adult: 19-44 years Female ab: Keloids are a dermal fibroproliferative disorder and can arise from trauma, acne, vaccination, and herpes zoster. Pyoderma gangrenosum (PG) is a painful ulcerative skin disorder that is associated with neutrophilic dysfunction. However, the pathophysiologies of keloids and PG are not fully understood. The authors encountered an unusual case of a 24-year-old woman who presented with an anterior chest keloid that bore an ulcer. The keloid was resected along with the ulcer, and histology revealed the ulcer to be a neutrophilic PG ulcer. A year after surgery, another ulcer developed in the scar. The ulcer met the PARACELSUS criteria of a postsurgical PG ulcer. After treatment with systemic prednisone and adalimumab for 250 days, the ulcer re-epithelialized. However, relapsed keloids were then observed at the PG site. Corticosteroid taping may be the safest therapy for patients with a history of PG. Conversely, if there is suspicion that a patient is prone to keloid development, diagnostic biopsies and surgical management of PG ulcers should be avoided or conducted with care. pubtype: Academic Journal doctype: case study pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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