Phase Angle but Not Psoas Muscle Predicts Nutritional Risk and Prognosis in Males with Hepatocellular Carcinoma.
Despite those with hepatocellular carcinoma (HCC) being at increased risk of malnutrition, there is a notable absence of practical approaches for nutritional assessment in clinical practice. We investigated the usefulness of phase angle (PhA) and Total Psoas Area Index (TPAI) for indicating nutritio...
| Publicado en: | Nutrition & Cancer Vol. 76; no. 10; pp. 963 - 974 |
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| Autores principales: | , , , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179805493&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179805493 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01635581 7MS jtl: Nutrition & Cancer issn: 01635581 maglogo: N pubinfo: dt: 2024 vid: 76 iid: 10 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 179805493 178455812 179805493 179805493 10.1080/01635581.2024.2378504 179805493 ppf: 963 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Phase Angle but Not Psoas Muscle Predicts Nutritional Risk and Prognosis in Males with Hepatocellular Carcinoma. aug: au: Pagano, Ana Paula Sicchieri, Juliana Maria Faccioli Morgado, Alexandre Souto de Moraes Meira Filho, Luiz Fernando Gonzalez, Maria Cristina Prado, Carla M. Elias Junior, Jorge Teixeira, Andreza Correa Chiarello, Paula Garcia affil: Hospital das Clínicas, Ribeirão Preto Medical School, Department of Health Sciences, Division of Nutrition and Metabolism, University of São Paulo, Ribeirão Preto, Brazil sug: subj: Carcinoma, Hepatocellular Prognosis Carcinoma, Hepatocellular Risk Factors Malnutrition Complications Prediction Models Psoas Muscles Pathology Psoas Muscles Radiography Nutritional Assessment Nutritional Status Magnetic Resonance Imaging Risk Assessment Human Male Middle Age Aged Brazil Hospitals Cross Sectional Studies Survival Analysis Anthropometry Muscle, Skeletal Physiology Body Composition Body Weight Body Height Body Mass Index Grip Strength Electric Impedance Spectrum Analysis T-Tests Analysis of Variance Pearson's Correlation Coefficient ROC Curve Kaplan-Meier Estimator Statistical Significance Data Analysis Software Descriptive Statistics Funding Source Middle Aged: 45-64 years Aged: 65+ years Male ab: Despite those with hepatocellular carcinoma (HCC) being at increased risk of malnutrition, there is a notable absence of practical approaches for nutritional assessment in clinical practice. We investigated the usefulness of phase angle (PhA) and Total Psoas Area Index (TPAI) for indicating nutritional risk and HCC prognosis. Weight, height, body mass index (BMI), adductor pollicis muscle thickness (APMT), and handgrip strength (HGS) were assessed. The Nutritional Risk Index (NRI) was calculated. Body composition was assessed using bioimpedance spectroscopy and magnetic resonance imaging. The Child-Turcotte-Pugh (CTP) score and Barcelona-Clinic Liver Cancer (BCLC) classification determined the prognosis. Fifty-one males with HCC were enrolled (CTP C = 11.8%). PhA showed a moderate positive correlation with APMT (r = 0.450; p < 0.001) and HGS (r = 0.418; p = 0.002) and a weak positive correlation with TPAI (r = 0.332; p = 0.021). PhA had a strong positive correlation with NRI (r = 0.614; p < 0.001). Mean PhA values were significantly different according to disease severity (CTP C p = 0.001, and BCLC D p = 0.053). TPAI had no significant correlation with HGS, CTP, or BCLC. PhA was a superior approach for predicting nutritional risk and prognosis in HCC than TPAI. Lower PhA is associated with disease progression, lower muscle mass and function, greater severity of nutritional risk, and increased mortality in HCC. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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