Review on Recent Advance of 3DP‐Based Pediatric Drug Formulations.

Three‐dimensional printing (3DP) has emerged as a game‐changing technology in the pharmaceutical industry, providing novel formulation development in the pharmaceutical sector as a whole, which improved patients' individualized therapy. The pediatric population is among the key targets for individua...

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Publicado en:BioMed Research International Vol. 2024; pp. 1 - 25
Autores principales: Tegegne, Aychew Mekuriaw, Ayenew, Kassahun Dires, Selam, Muluken Nigatu, Baralla, Elena
Formato: pictorial review tables/charts Journal Article
Publicado: Wiley-Blackwell 9/26/2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 9/26/2024
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      pub: Wiley-Blackwell
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        10.1155/2024/4875984
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        atl: Review on Recent Advance of 3DP‐Based Pediatric Drug Formulations.
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        au:
          Tegegne, Aychew Mekuriaw
          Ayenew, Kassahun Dires
          Selam, Muluken Nigatu
          Baralla, Elena
        affil: Department of Pharmacy,, Medicine and Health Science College,, Debre Berhan University,, Debre Berhan, Ethiopia, dbu.edu.et
      sug:
        subj:
          Printing, Three-Dimensional Utilization
          Chemistry, Pharmaceutical
          Pediatrics
          Individualized Medicine
          Drug Design
          Dosage Forms
          Formularies
          Pediatric Care
          Drug Compounding
      ab: Three‐dimensional printing (3DP) has emerged as a game‐changing technology in the pharmaceutical industry, providing novel formulation development in the pharmaceutical sector as a whole, which improved patients' individualized therapy. The pediatric population is among the key targets for individualized therapy. Children are a diverse group that includes neonates, infants, and toddlers, each with unique physiological characteristics. Treatment adherence has a significant impact on safe and effective pharmacotherapy in the pediatric population. Improvement of therapeutic dosage forms that provide for the special demands of the pediatric population is a significant challenge for the pharmaceutical industry. Scientists have actively explored 3DP, a quick prototype manufacturing method that has emerged in recent years from many occupations due to its benefits of modest operation, excellent reproducibility, and vast adaptability. This review illuminates the most widely used 3DP technology and its application in the development of pediatric‐friendly drug formulations. This 3DP technology allows optimization of pediatric dosage regimens and cases that require individualized treatment, such as geriatrics, renal impairment, liver impairment, critically ill, pregnancy populations, and drugs with nonlinear pharmacokinetics. The fast evolution of 3DP expertise, in addition to the introduction of pharmaceutical inks, has enormous promise for patient dosage form customization.
      pubtype: Academic Journal
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        review
        tables/charts
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      ougenre: Article
    language: English
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