AUDIT C compared to PEth in middle-aged volunteers.

Aims To compare Alcohol Use Disorders Identification Test (AUDIT C) to phosphatidylethanol (PEth) in middle-aged randomly selected volunteers. Apply previously suggested lower cut-offs for PEth using moderate alcohol intake according to AUDIT C as a reference. Methods Within the Swedish CardioPulmon...

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Publicado en:Alcohol & Alcoholism Vol. 59; no. 5; pp. 1 - 8
Autores principales: Fredriksson, Marie, Werner, Mårten
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Sep2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2024
      vid: 59
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      pub: Oxford University Press / USA
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        10.1093/alcalc/agae048
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        atl: AUDIT C compared to PEth in middle-aged volunteers.
      aug:
        au:
          Fredriksson, Marie
          Werner, Mårten
        affil: Department of Public Health and Clinical Medicine, Umeå University , Umeå , Sweden
      sug:
        subj:
          Alcohol-Related Disorders
          Substance Use Disorders In Middle Age
          Phospholipids Blood
          Cardiovascular Diseases
          Human
          Middle Age
          Aged
          Sweden
          Male
          Female
          Self Report
          Descriptive Statistics
          Volunteer Workers
          Funding Source
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Aims To compare Alcohol Use Disorders Identification Test (AUDIT C) to phosphatidylethanol (PEth) in middle-aged randomly selected volunteers. Apply previously suggested lower cut-offs for PEth using moderate alcohol intake according to AUDIT C as a reference. Methods Within the Swedish CardioPulmonary BioImage Study, 2255 middle-aged (50–64 years of age) volunteers in northern Sweden participated in comparing AUDIT C to PEth 16:0/18:1. Results There was a moderate correlation between PEth 16:0/18:1 and AUDIT C (r  = 0.66). None of the participants with the AUDIT C-score 0 had a measurable PEth. Of moderate alcohol consumers, according to AUDIT C (AUDIT C 1–3 women, 1–4 men), 96% had a PEth below 0.3 μmol/L, 91% had a PEth below 0.16 μmol/L, and 84% had a PEth below 0.11 μmol/L. With PEth equivalent to excessive alcohol consumption (≥0.3 μmol/L), 26% had an AUDIT C-score below excessive alcohol consumption (<4 for women and <5 for men). Thirty percent of patients with a PEth ≥0.16 μmol/L had an AUDIT C-score below excessive alcohol consumption, and 37% had a PEth ≥0.11 μmol/L. We found no significant correlation between BMI and PEth or AUDIT C. Conclusions There is a significant correlation between AUDIT C and PEth. Using AUDIT C alone, 26% of high-consumers, according to PEth, are not found in our cohort, but an AUDIT C-score of 0 will exclude high consumption, according to PEth. Our findings support the current cut-off for PEth of 0.3 μmol/L, but a lower cut-off seems reasonable.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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