Engagement in Care, Awareness, and Interest in Long-Acting Injectable Anti-Retroviral Therapy.

Long Acting Injectable (LAI) therapy to treat HIV is an alternative to daily oral medications. The success of early roll-out of LAI to eligible patients requires a better understanding of patients' awareness and interest in this novel therapy. We administered an electronic survey to patients attendi...

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Publicado en:AIDS & Behavior Vol. 28; no. 10; pp. 3315 - 3326
Autores principales: Stout, Jacob A., Allamong, Maxwell, Hung, Frances, Link, Katherine, Chan, Cliburn, Muiruri, Charles, Sauceda, John, McKellar, Mehri S.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
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      pub: Springer Nature
      place: New York, New York
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        atl: Engagement in Care, Awareness, and Interest in Long-Acting Injectable Anti-Retroviral Therapy.
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        au:
          Stout, Jacob A.
          Allamong, Maxwell
          Hung, Frances
          Link, Katherine
          Chan, Cliburn
          Muiruri, Charles
          Sauceda, John
          McKellar, Mehri S.
        affil: Duke University School of Medicine, Durham, NC, USA
      sug:
        subj:
          Delayed-Action Preparations
          Antiretroviral Therapy, Highly Active
          Knowledge
          Human United States
          Funding Source
          United States
          Surveys
          Descriptive Statistics
          Confidence Intervals
          Odds Ratio
          Male
          Female
          Adult
          Middle Age
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Long Acting Injectable (LAI) therapy to treat HIV is an alternative to daily oral medications. The success of early roll-out of LAI to eligible patients requires a better understanding of patients' awareness and interest in this novel therapy. We administered an electronic survey to patients attending an urban HIV clinic in the US South. Eligible participants were 18 + years old with a most recent HIV-1 viral load < 200 copies/ml, without any evidence of genotypic resistance to LAI components or chronic hepatitis B. Survey recipients were asked about current treatment, engagement in care, and knowledge of LAI. Between January-April 2023, 480 patients were screened; 319 were eligible, and 155 (49%) completed the survey. The majority (119, 77%) were aware of, and 87 (56%) were interested in LAI. In regression analysis, only age was associated with interest in LAI (OR 0.95, 95% CI 0.92,0.99). Among proposed benefits of injectables, ease of travel without pills, lack of daily pill-taking, and fewer medication interactions were most appealing. Among proposed concerns with injectables, higher cost and insurance coverage of the new medicine were most worrisome. A large majority of people with HIV (PWH) are aware of the newest treatment available, and just over half of our sample expressed interest in LAI. Older age was associated with lower interest in LAI. LAI is appealing for its convenience, privacy, and avoidance of drug interactions, while the increased costs associated with LAI need to be addressed.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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