Syndemic Psychosocial Conditions among Youth Living with HIV: a Latent Class Analysis.

Drug use, mental distress, and other psychosocial factors threaten HIV care for youth living with HIV (YLWH). We aimed to identify syndemic psychosocial patterns among YLWH and examine how such patterns shape HIV outcomes. Using baseline data from 208 YLWH enrolled in an HIV treatment adherence inte...

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Publicado en:AIDS & Behavior Vol. 28; no. 10; pp. 3498 - 3512
Autores principales: Wiginton, John Mark, Amico, K. Rivet, Hightow-Weidman, Lisa, Sullivan, Patrick, Horvath, Keith J.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
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      place: New York, New York
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        10.1007/s10461-024-04427-7
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        atl: Syndemic Psychosocial Conditions among Youth Living with HIV: a Latent Class Analysis.
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          Wiginton, John Mark
          Amico, K. Rivet
          Hightow-Weidman, Lisa
          Sullivan, Patrick
          Horvath, Keith J.
        affil: https://ror.org/0168r3w48 Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California-San Diego, 9500 Gilman Drive, 92093-0507, La Jolla, CA, USA
      sug:
        subj:
          HIV Infections Epidemiology
          HIV Infections Psychosocial Factors
          HIV Infections Drug Therapy
          Continuity of Patient Care
          Treatment Outcomes
          Medication Compliance
          Human
          Funding Source
          Structural Equation Modeling
          Stigma
          Depression
          Anxiety
          Alcohol Abuse
          Cannabis
          Street Drugs
          Housing Instability
          Multiple Logistic Regression
          Young Adult
          Adolescence
          Cisgender Persons
          Male
          Female
          United States
          Adolescent: 13-18 years
          Male
          Female
      ab: Drug use, mental distress, and other psychosocial factors threaten HIV care for youth living with HIV (YLWH). We aimed to identify syndemic psychosocial patterns among YLWH and examine how such patterns shape HIV outcomes. Using baseline data from 208 YLWH enrolled in an HIV treatment adherence intervention, we performed latent class analysis on dichotomized responses to 9 psychosocial indicators (enacted HIV stigma; clinical depression and anxiety; alcohol, marijuana, and illicit drug misuse; food and housing insecurity; legal history). We used multinomial logistic regression to assess latent class-demographic associations and the automatic Bolck-Croon-Hagenaars method to assess HIV outcomes by class. Mean age of participants was 21 years; two thirds identified as cis male, 60% were non-Hispanic Black, and half identified as gay. Three classes emerged: "Polydrug-Socioeconomic Syndemic" (n = 29; 13.9%), "Distress-Socioeconomic Syndemic" (n = 35, 17.1%), and "Syndemic-free" (n = 142, 69.0%). Older, unemployed non-students were overrepresented in the "Polydrug-Socioeconomic Syndemic" class. Missed/no HIV care appointments was significantly higher in the "Polydrug-Socioeconomic Syndemic" class (81.4%) relative to the "Syndemic-free" (32.8%) and "Distress-Socioeconomic Syndemic" (31.0%) classes. HIV treatment nonadherence was significantly higher in the "Polydrug-Socioeconomic Syndemic" class (88.5%) relative to the "Syndemic-free" class (59.4%) but not the "Distress-Socioeconomic Syndemic" class (70.8%). Lack of HIV viral load suppression was non-significantly higher in the "Polydrug-Socioeconomic Syndemic" class (29.7%) relative to the "Syndemic-free" (16.2%) and "Distress-Socioeconomic Syndemic" (15.4%) classes. Polydrug-using, socioeconomically vulnerable YLWH are at risk for adverse HIV outcomes, warranting tailored programming integrated into extant systems of HIV care.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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