Spatial lung imaging in clinical and translational settings.

For many severe lung diseases, non-invasive biomarkers from imaging could improve early detection of lung injury or disease onset, establish a diagnosis, or help follow-up disease progression and treatment strategies. Imaging of the thorax and lung is challenging due to its size, respiration movemen...

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Publicado en:Breathe Vol. 20; no. 3; pp. 1 - 12
Autores principales: Mahmutovic Persson, Irma, Bozovic, Gracijela, Westergren-Thorsson, Gunilla, Rolandsson Enes, Sara
Formato: diagnostic images exam questions pictorial review tables/charts Journal Article
Publicado: European Respiratory Society Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
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      pub: European Respiratory Society
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        atl: Spatial lung imaging in clinical and translational settings.
      aug:
        au:
          Mahmutovic Persson, Irma
          Bozovic, Gracijela
          Westergren-Thorsson, Gunilla
          Rolandsson Enes, Sara
        affil: Lund University BioImaging Centre (LBIC), Faculty of Medicine, Lund University, Lund, Sweden
      sug:
        subj:
          Lung Diseases Radiography
          Diagnostic Imaging Methods
          Imaging, Three-Dimensional
          Radiographic Image Enhancement
          Artificial Intelligence
          Machine Learning
      ab: For many severe lung diseases, non-invasive biomarkers from imaging could improve early detection of lung injury or disease onset, establish a diagnosis, or help follow-up disease progression and treatment strategies. Imaging of the thorax and lung is challenging due to its size, respiration movement, transferred cardiac pulsation, vast density range and gravitation sensitivity. However, there is extensive ongoing research in this fast-evolving field. Recent improvements in spatial imaging have allowed us to study the three-dimensional structure of the lung, providing both spatial architecture and transcriptomic information at single-cell resolution. This fast progression, however, comes with several challenges, including significant image file storage and network capacity issues, increased costs, data processing and analysis, the role of artificial intelligence and machine learning, and mechanisms to combine several modalities. In this review, we provide an overview of advances and current issues in the field of spatial lung imaging.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        exam questions
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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