Differential Effects of the Zn-His-Bkb vs Zn-His-[Asp/Glu] Triad on Zn-Core Stability and Reactivity.
The most common partner of the Zn-bound His is the Asp/Glu carboxylate side chain in catalytic Zn sites and the backbone (Bkb) carbonyl group in structural Zn sites. To elucidate the factors governing the selection of the second-shell partner of the Zn-bound His in structural/catalytic Zn sites, sys...
| Publicado en: | Journal of the American Chemical Society Vol. 127; no. 32; pp. 11336 - 11348 |
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| Autores principales: | , , |
| Formato: | Artículo |
| Publicado: |
American Chemical Society
8/17/2005
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |