Long-term clinical outcomes in patients with hypertrophic cardiomyopathy versus hypertensive heart disease.
Background: For most patients with hypertrophic cardiomyopathy (HCM), the clinical course is considered relatively benign, similar to hypertensive heart disease (HHD). We compared the long-term outcomes in patients with HCM versus HHD from a large healthcare system database. Methods: Data from SSM V...
| Published in: | Baylor University Medical Center Proceedings Vol. 37; no. 6; pp. 916 - 922 |
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| Main Authors: | , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
Nov2024
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=180359104&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 180359104 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08998280 1XEP jtl: Baylor University Medical Center Proceedings issn: 08998280 maglogo: N pubinfo: dt: Nov2024 vid: 37 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 180359104 179660634 180359104 180359104 10.1080/08998280.2024.2402153 180359104 ppf: 916 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Long-term clinical outcomes in patients with hypertrophic cardiomyopathy versus hypertensive heart disease. aug: au: Park, William D. Chrusciel, Timothy Verma, Divya R. Benjamin, Mina M. affil: School of Medicine, Saint Louis University, St. Louis, Missouri, USA sug: subj: Heart Diseases Diagnosis Cardiomyopathy, Hypertrophic Diagnosis Hypertension Diagnosis Cardiomyopathy, Hypertrophic Prognosis Hypertension Prognosis Heart Diseases Prognosis Hospitalization Resource Databases Treatment Outcomes Human Age Factors Sex Factors Race Factors Heart Failure Risk Factors Tachycardia, Ventricular Ventricular Fibrillation Patient Admission Pacemaker, Artificial Defibrillators, Implantable Comorbidity Odds Ratio Descriptive Statistics Confidence Intervals Survival Analysis Retrospective Design Record Review Comparative Studies Risk Assessment ab: Background: For most patients with hypertrophic cardiomyopathy (HCM), the clinical course is considered relatively benign, similar to hypertensive heart disease (HHD). We compared the long-term outcomes in patients with HCM versus HHD from a large healthcare system database. Methods: Data from SSM Virtual Data Warehouse were used to identify patients with a new diagnosis of either HCM or HHD who followed up in our system for at least 6 months. HCM patients were matched 1:1 to HHD patients based on age, sex, and race. Outcomes examined included heart failure (HF) admission, ventricular tachyarrhythmia (ventricular fibrillation or sustained ventricular tachycardia), and need for pacemaker or defibrillator implantation. We identified 1904 HCM patients along with HHD controls. Results: After adjusting for demographic characteristics and relevant comorbidities, HCM had higher odds of HF admission (odds ratio [OR]: 1.73, 95% confidence interval [CI]: 1.43–2.10), ventricular tachyarrhythmias (OR: 2.31, CI: 1.60–3.33), pacemaker implantation (OR: 2.14, CI: 1.29–3.57), and defibrillator implantation (OR: 3.77, CI: 1.82–7.83). Survival analysis confirmed the difference in outcomes early on from the time of diagnosis. Conclusion: In this retrospective study from a large healthcare system database, HCM patients had significantly higher incidences of HF admission, ventricular tachyarrhythmias, and pacemaker or defibrillator implantation compared to HHD patients. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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