First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues.

Purpose: Multidrug resistance-associated protein 1 (MRP1) is a transport protein with a widespread tissue distribution, which has been implicated in the pathophysiology of Alzheimer's and chronic respiratory disease. PET with 6-bromo-7-[11C]methylpurine ([11C]BMP) has been used to measure MRP1 funct...

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Publicado en:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 51; no. 13; pp. 3900 - 3912
Autores principales:	Mairinger, Severin, Jackwerth, Matthias, Chalampalakis, Zacharias, Rausch, Ivo, Weber, Maria, Wölfl-Duchek, Michael, Pracher, Lena, Nics, Lukas, Pahnke, Jens, Langsteger, Werner, Hacker, Marcus, Zeitlinger, Markus, Langer, Oliver
Formato:	Journal Article
Publicado:	Springer Nature Nov2024
Acceso en línea:	Ver este registro en EBSCOhost