Brain activation in older adults with hypertension and normotension during standing balance task: an fNIRS study.

Background: Hypertension (HT) is a common chronic disease in older adults. It not only leads to dizziness and other symptoms affecting balance in older adults with HT but also affects the hemodynamics of the cerebral cortex. At present, potential neural mechanisms of balance control in older adults...

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Publicado en:Frontiers in Aging Neuroscience pp. 1 - 11
Autores principales: Weichao Fan, Qing Zeng, Peng Zheng, Shuyang Wen, Gege Li, Tao Fan, Guozhi Huang, Manxu Zheng, Qinglu Luo
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Frontiers Media S.A. 2024
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Frontiers in Aging Neuroscience
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      dt: 2024
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      pub: Frontiers Media S.A.
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        10.3389/fnagi.2024.1458494
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        atl: Brain activation in older adults with hypertension and normotension during standing balance task: an fNIRS study.
      aug:
        au:
          Weichao Fan
          Qing Zeng
          Peng Zheng
          Shuyang Wen
          Gege Li
          Tao Fan
          Guozhi Huang
          Manxu Zheng
          Qinglu Luo
        affil: Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
      sug:
        subj:
          Brain Physiology
          Hypertension
          Standing
          Balance, Postural
          Task Performance and Analysis
          Spectroscopy, Near-Infrared
          Cerebral Cortex Physiology
          Human China
          Funding Source
          Cross Sectional Studies
          Hemodynamics
          Proprioception
          Accidental Falls Prevention and Control
          Scales
          China
          Kinematics
          Descriptive Statistics
          Data Analysis Software
          T-Tests
          Chi Square Test
          Causal Modeling
          Body Mass Index
          Comorbidity
          Nonparametric Statistics
          Male
          Female
          Aged
          Aged, 80 and Over
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: Hypertension (HT) is a common chronic disease in older adults. It not only leads to dizziness and other symptoms affecting balance in older adults with HT but also affects the hemodynamics of the cerebral cortex. At present, potential neural mechanisms of balance control in older adults with HT are still unclear. Therefore, this study aimed to explore the differences in the center of pressure (COP) and cerebral cortex activation between older adults with HT and normotension (NT) during standing balance tasks. This study May provide guidance for the early detection of the risk of falls among older adults with HT and the development of clinical rehabilitation strategies. Methods: In this cross-sectional study, 30 older adults with NT (NT group) and 27 older adults with HT (HT group) were subjected to three conditions: task 1, standing with eyes open on a stable surface; task 2, standing with eyes closed on a stable surface; and task 3, standing with eyes open on the surface of the foam pad. Cortical hemodynamic reactions were measured using functional near-infrared spectroscopy, and COP parameters were measured using a force plate. Results: The mean velocity of the COP in the medial–lateral direction in the NT group was significantly higher than that in the HT group (F  =  5.955, p  =  0.018) during task 3. When proprioception was disturbed, the activation of the left premotor cortex and supplementary motor cortex in the HT group was significantly lower than that in the NT group (F  =  14.381, p  <  0.001). Conclusion: The standing balance function of older adults with HT does not appear to be worse based on COP parameters than those of older adults with NT. This study revealed that the changes in the central cortex related to standing balance appear to be more indicative of balance control deficits in older adults with HT than changes in peripheral COP parameters, suggesting the importance of the early evaluation of cortical activation in older adults with HT at risk of falls.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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