Etiologies of atrioventricular block in young patients: A single‐center study in China.

Background: Atrioventricular block (AVB) is common in the elderly and therefore considered to be a degenerative disease of the cardiac conduction system. However, there exist other etiologies contributing to AVB in young patients. This study aimed to determine the etiologies in patients aged before...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 47; no. 11; pp. 1521 - 1528
Autores principales: Zheng, Jianhong, Chen, Xin, Luo, Guanhao, Zhang, Qianhuan, Liao, Hongtao, Deng, Hai, Fang, Xianhong, Xue, Yumei, Liu, Yang, Wu, Shulin
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2024
      vid: 47
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/pace.15067
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        atl: Etiologies of atrioventricular block in young patients: A single‐center study in China.
      aug:
        au:
          Zheng, Jianhong
          Chen, Xin
          Luo, Guanhao
          Zhang, Qianhuan
          Liao, Hongtao
          Deng, Hai
          Fang, Xianhong
          Xue, Yumei
          Liu, Yang
          Wu, Shulin
        affil: School of Medicine, South China University of Technology, Guangzhou, China
      sug:
        subj:
          Heart Block Etiology
          Pacemaker, Artificial
          Human
          Retrospective Design
          China
          Record Review
          Cardiac Surgery Adverse Effects
          Myocardial Diseases Complications
          Myocardial Infarction Complications
          Sex Factors
          Male
          Female
          Cardiomyopathy, Dilated Complications
          Age Factors
          Catheter Ablation Adverse Effects
          Adult
          Middle Age
          Atrial Fibrillation Complications
          Atrial Flutter Complications
          Descriptive Statistics
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Atrioventricular block (AVB) is common in the elderly and therefore considered to be a degenerative disease of the cardiac conduction system. However, there exist other etiologies contributing to AVB in young patients. This study aimed to determine the etiologies in patients aged before 60 years receiving their first pacemaker implantation for AVB in China. Methods and Results: Medical records and diagnostic tests of AVB patients were reviewed to identify the etiologies between 2010 and 2021 at Guangdong Provincial People's Hospital. Eight hundred and twenty‐six patients (median age 47 years; 47.9% males) were included. The etiologies were identified in 336 (40.7%) cases, including complications to cardiac surgery (n = 190 [23.0%]), myocarditis (n = 57 [6.9%]), myocardial infarction (n = 25 [3.0%]), complications to catheter‐based interventional procedures (n = 21 [2.5%]) and others (n = 43 [5.2%]). AVB caused by myocardial infarction was more common in men (5.8% vs. 0.5%, p <.001), while women received pacing treatment earlier (48 vs. 46 years, p =.019). Men were more likely to suffer from dilated cardiomyopathy (6.6% vs. 2.1%, p =.001) and atrial fibrillation/flutter (23.0% vs. 12.8%, p <.001). The number of first pacemaker implantation increased with age especially among patients with unclear etiologies. Conclusion: The etiology of AVB was only determined in approximately 40% of patients receiving their first pacemaker implantation aged before 60 years. The predominance of AVB with unknown etiology and potential gender differences warrants further studies.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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