Radical Hydroxyalkylation of C-H Bond Adjacent to Nitrogen of Tertiary Amides, Ureas, and Amines.
The article discusses radical hydroxyalkylation of carbon-hydrogen (C-H) bond adjacent to Nitrogen of tertiary amides, ureas and amines. The authors show that several tertiary amides, ureas, and amines undergo direct intermolecular addition to aldehydes under the EtB/air conditions, thereby providin...
| Publicado en: | Journal of the American Chemical Society Vol. 127; no. 33; pp. 11610 - 11612 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Chemical Society
8/24/2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=18069307&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 18069307 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00027863 ACS jtl: Journal of the American Chemical Society issn: 00027863 maglogo: N pubinfo: dt: 8/24/2005 vid: 127 iid: 33 pid: 997 pub: American Chemical Society artinfo: ui: 18069307 10.1021/ja053855q ppf: 11610 ppct: 2 formats: tig: atl: Radical Hydroxyalkylation of C-H Bond Adjacent to Nitrogen of Tertiary Amides, Ureas, and Amines. aug: au: Yoshimitsu, Takehiko Arano, Yoshimasa Nagaoka, Hiroto affil: Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan. su: Chemical bonds Nitrogen Amides Urease Amines Aldehydes sug: subj: Chemical bonds Nitrogen Amides Urease Amines Aldehydes ab: The article discusses radical hydroxyalkylation of carbon-hydrogen (C-H) bond adjacent to Nitrogen of tertiary amides, ureas and amines. The authors show that several tertiary amides, ureas, and amines undergo direct intermolecular addition to aldehydes under the EtB/air conditions, thereby providing a unique and simple means for the radical sp C-H transformation of nitrogen-containing molecules. The amounts of C-H substrate and EtB influenced the efficiency of the reaction. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2005 holdings: @attributes: islocal: N |
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