Respiratory-Swallow Coordination and Its Relationship With Pharyngeal Residue, Penetration, and Aspiration in People With Parkinson's Disease.

Purpose: Respiratory-swallow coordination (RSC) frequently changes in people with Parkinson's disease (PwPD). Little is known about how these changes relate to impairments in swallowing safety (penetration and aspiration) and efficiency (pharyngeal residue). Therefore, the aims of this study were to...

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Publicado en:Journal of Speech, Language & Hearing Research Vol. 67; no. 11; pp. 4314 - 4339
Autores principales: Curtis, James A., Borders, James C., Kiefer, Brianna, Alcalay, Roy N., Huber, Jessica E., Troche, Michelle S.
Formato: Artículo
Publicado: American Speech-Language-Hearing Association Nov2024
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2024
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      pub: American Speech-Language-Hearing Association
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        10.1044/2024_JSLHR-24-00056
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        atl: Respiratory-Swallow Coordination and Its Relationship With Pharyngeal Residue, Penetration, and Aspiration in People With Parkinson's Disease.
      aug:
        au:
          Curtis, James A.
          Borders, James C.
          Kiefer, Brianna
          Alcalay, Roy N.
          Huber, Jessica E.
          Troche, Michelle S.
        affil:
          Aerodigestive Innovations Research Lab, Department of Otolaryngology-Head & Neck Surgery, Weill Cornell Medicine, Cornell University, New York, NY
          Laboratory for the Study of Upper Airway Dysfunction, Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY
          Department of Physical Medicine and Rehabilitation, University of California Davis Medical Center, Sacramento
          Neurological Institute, Division of Movement Disorders, Department of Neurology, Columbia University Irving Medical Center, New York, NY
          Neurological Institute, Division of Movement Disorders, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
          Speech Physiology Laboratory, Department of Communicative Disorders and Sciences, University at Buffalo, NY
      su:
        United States
        Cross-sectional method
        Plethysmography
        Nasal cavity
        Statistical models
        Data analysis
        Respiration
        Functional assessment
        Parkinson's disease
        Respiratory aspiration
        Descriptive statistics
        Pharynx
        Odds ratio
        Lung volume measurements
        Endoscopic gastrointestinal surgery
        Statistics
        Deglutition
        Comparative studies
        Data analysis software
        Deglutition disorders
        Inter-observer reliability
      sug:
        subj:
          Cross-sectional method
          United States
          Plethysmography
          Nasal cavity
          Statistical models
          Data analysis
          Respiration
          Functional assessment
          Parkinson's disease
          Respiratory aspiration
          Descriptive statistics
          Pharynx
          Odds ratio
          Lung volume measurements
          Endoscopic gastrointestinal surgery
          Statistics
          Deglutition
          Comparative studies
          Data analysis software
          Deglutition disorders
          Inter-observer reliability
      ab: Purpose: Respiratory-swallow coordination (RSC) frequently changes in people with Parkinson's disease (PwPD). Little is known about how these changes relate to impairments in swallowing safety (penetration and aspiration) and efficiency (pharyngeal residue). Therefore, the aims of this study were to assess the relationships between RSC, pharyngeal residue, penetration, and aspiration in PwPD. Method: Twenty-four PwPD were recruited to undergo simultaneous assessment of RSC, swallowing safety, and swallowing efficiency. RSC was assessed using respiratory inductive plethysmography and nasal airflow and included measurements of respiratory pause duration, respiratory phase patterning, and lung volume during swallowing. Swallowing safety and efficiency were assessed using flexible endoscopic evaluation of swallowing, analyzed using the Visual Analysis of Swallowing Efficiency and Safety, and included measurements of pharyngeal residue, penetration, and aspiration. All data were blindly analyzed, with 20% of the data repeated for interrater reliability assessment. Multilevel statistical models were used to examine the relationships between RSC and swallowing. Results: A total of 812 swallows were analyzed from 24 participants. Only 33.4% of swallows exhibited the typical exhale-swallow-exhale pattern. Additionally, 95% of participants exhibited abnormal swallow function. More severe hypophar-yngeal residue ratings were associated with inhaling before the swallow compared to exhaling before the swallow. Additionally, more severe events of penetration and aspiration were associated with (a) inhaling before the swallow compared to exhaling before the swallow, (b) inhaling after the swallow compared to exhaling after the swallow, and (c) longer swallow-related respiratory pause durations. Inhaling after the swallow exhibited the strongest relationship with impairments in swallowing safety when compared to all other RSC variables. Conclusions: RSC exhibited significant relationships with pharyngeal residue, penetration, and aspiration in these PwPD. Clinicians should attend to RSC when assessing swallowing in PwPD. Future research is needed to examine if training an exhale-swallow-exhale pattern can be used to improve disordered swallowing in PwPD.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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