Longitudinal change in neurocognitive functioning in children and adolescents at clinical high risk for psychosis: a systematic review.
Clinical high risk of psychosis (CHR-P) population has become an attractive area of interest in preventing transitions to psychosis. The consequences of developing a psychotic disorder may be worse in cases of early onset. Thus, childhood and adolescence represent a critical developmental window, wh...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 33; no. 10; pp. 3377 - 3388 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=180935255&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 180935255 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Oct2024 vid: 33 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 180935255 163778704 180935255 180935255 10.1007/s00787-023-02221-9 180935255 ppf: 3377 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Longitudinal change in neurocognitive functioning in children and adolescents at clinical high risk for psychosis: a systematic review. aug: au: Pedruzo, Borja Aymerich, Claudia Pacho, Malein Herrero, Jon Laborda, María Bordenave, Marta Giuliano, Anthony J. McCutcheon, Robert A. Gutiérrez-Rojas, Luis McGuire, Philip Stone, William S. Fusar-Poli, Paolo González-Torres, Miguel Ángel Catalan, Ana affil: Department of Psychiatry, Basurto University Hospital, Bilbao, Spain sug: subj: Cognition Disorders In Infancy and Childhood Cognition Disorders In Adolescence Psychotic Disorders Risk Factors Risk Assessment Human Systematic Review Child Adolescence Male Female Executive Function Learning Attention Antipsychotic Agents Therapeutic Use Age of Onset Child: 6-12 years Adolescent: 13-18 years Male Female ab: Clinical high risk of psychosis (CHR-P) population has become an attractive area of interest in preventing transitions to psychosis. The consequences of developing a psychotic disorder may be worse in cases of early onset. Thus, childhood and adolescence represent a critical developmental window, where opportunities to gain social and adaptive abilities depend on the individuals' neurocognitive performance. There have been previous syntheses of the evidence regarding neurocognitive functioning in CHR-P individuals and its longitudinal changes. However, there has been less focus on children and adolescents at CHR-P. A multistep literature search was performed from database inception until July 15th, 2022. PRIMSA/MOOSE compliant systematic review and PROSPERO protocol were used to identify studies reporting on longitudinal changes in neurocognitive functioning in children and adolescents (mean age of sample ≤ 18 years) at CHR-P and matched healthy control (HC) group. A systematic review of identified studies was then undertaken. Three articles were included, resulting in a total sample size of 151 CHR-P patients [mean (SD) age, 16.48 (2.41) years; 32.45% female] and 64 HC individuals [mean (SD) age, 16.79 (2.38) years; 42.18% female]. CHR-P individuals had worse outcomes in verbal learning, sustained attention and executive functioning domains compared to HC. Individuals taking antidepressants had better outcomes in verbal learning in contrast with those taking antipsychotics. In children and adolescents, neurocognition may be already impaired before the psychosis onset, and remains stable during the transition to psychosis. Further study should be performed to obtain more robust evidence. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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