Empagliflozin-activated AMPK elicits neuroprotective properties in reserpine-induced depression via regulating dynamics of hippocampal autophagy/inflammation and PKCζ-mediated neurogenesis.

Rationale: Major depression has been an area of extensive research during the last decades, for it represents a leading cause of disability and suicide. The stark rise of depression rates influenced by life stressors, economic threats, pandemic era, and resistance to classical treatments, has made t...

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Bibliographic Details
Published in:Psychopharmacology Vol. 241; no. 12; pp. 2565 - 2585
Main Authors: Muhammad, Radwa N., Albahairy, Mohammed A., Abd El Fattah, Mai A., Ibrahim, Weam W.
Format: Journal Article
Published: Springer Nature Dec2024
Online Access:View this record in EBSCOhost