A retrospective cohort study of prescription drug use among youth with intellectual/developmental disabilities in British Columbia.

Background: People with intellectual/developmental disabilities (IDD) are known to have high rates of prescription drug use, particularly for psychotropic medications. This is of concern due to the many side effects associated with these medications and because of the risks of polypharmacy. In this...

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Published in:Journal of Intellectual Disability Research Vol. 68; no. 10; pp. 1156 - 1167
Main Authors: Marquis, S., Marquis, N. E., Lunsky, Y., McGrail, K. M., Baumbusch, J.
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Oct2024
Online Access:View this record in EBSCOhost
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      dt: Oct2024
      vid: 68
      iid: 10
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jir.13147
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        atl: A retrospective cohort study of prescription drug use among youth with intellectual/developmental disabilities in British Columbia.
      aug:
        au:
          Marquis, S.
          Marquis, N. E.
          Lunsky, Y.
          McGrail, K. M.
          Baumbusch, J.
        affil: School of Nursing, Faculty of Applied Science, University of British Columbia, Vancouver British Columbia,, Canada
      sug:
        subj:
          Intellectual Disability Epidemiology
          Developmental Disabilities Epidemiology
          Intellectual Disability Drug Therapy
          Developmental Disabilities Drug Therapy
          Drugs, Prescription
          Psychotropic Drugs Therapeutic Use
          Human
          Male
          Female
          Adolescence
          Young Adult
          Retrospective Design
          Prospective Studies
          Record Review
          British Columbia
          Odds Ratio
          Amoxicillin Therapeutic Use
          Albuterol Therapeutic Use
          Thyroxine Therapeutic Use
          Antidepressive Agents Therapeutic Use
          Antipsychotic Agents Therapeutic Use
          Antianxiety Agents, Benzodiazepine Therapeutic Use
          Adrenergic Antagonists Therapeutic Use
          Ganglionic Stimulants Therapeutic Use
          Descriptive Statistics
          Comparative Studies
          Funding Source
          Adolescent: 13-18 years
          Male
          Female
      ab: Background: People with intellectual/developmental disabilities (IDD) are known to have high rates of prescription drug use, particularly for psychotropic medications. This is of concern due to the many side effects associated with these medications and because of the risks of polypharmacy. In this paper we compare the most commonly dispensed drugs and all psychotropic medications for youth with IDD compared with youth without IDD. Methods: Using population‐level administrative health data over a 10‐year period, this study examined medications dispensed to youth with an IDD aged 15–24 years compared with youth without an IDD. The most common medications dispensed and the number of youth they were dispensed to were determined. As well a wide variety of psychotropic medications were examined. Results: There were a total of 20 591 youth with IDD and 1 293 791 youth without IDD identified. Youth with IDD had higher odds of being dispensed pain medications, amoxicillin, salbutamol, levothyroxine and all the psychotropic medications (antidepressants, antipsychotics, anxiolytics, anti‐adrenergic agents, mood stabilisers and stimulants). For youth with IDD, 6558 (31.85%) were dispensed two or more different psychotropic medications within a year, compared with 75 963 (5.87%) of youth without IDD. Discussion: Compared to youth without IDD, youth with IDD had significantly higher odds of being dispensed most of the prescription medications studied, including all of the psychotropic medications. They were also twice as likely to be dispensed two or more medications from different classes of psychotropic drugs within the same year. These findings have important implications for the health of people with IDD and for their health care providers.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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