The effects of upper cervical spine manual therapy on central sensitization and brainstem auditory evoked potentials in subjects with migraine and neck pain.

Migraine is an important disease due to its impact on global health. Due to association of neck pain with migraine, manual therapy (MT) often used in management. The aim of this study was to evaluate the effects of upper cervical spine MT on specific mechanisms including central sensitization (CS) a...

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Publicado en:Journal of Bodywork & Movement Therapies Vol. 40; pp. 184 - 190
Autores principales: Jafari, Mehdi, Bahrpeyma, Farid, Togha, Mansoureh, Vahabizad, Fahimeh, Hall, Toby
Formato: research randomized controlled trial Journal Article
Publicado: Churchill Livingstone, Inc. Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
      vid: 40
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      pub: Churchill Livingstone, Inc.
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        181035739
        10.1016/j.jbmt.2023.09.009
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        atl: The effects of upper cervical spine manual therapy on central sensitization and brainstem auditory evoked potentials in subjects with migraine and neck pain.
      aug:
        au:
          Jafari, Mehdi
          Bahrpeyma, Farid
          Togha, Mansoureh
          Vahabizad, Fahimeh
          Hall, Toby
        affil: Department of Physiotherapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
      sug:
        subj:
          Migraine Therapy
          Neck Pain Therapy
          Manual Therapy Methods
          Evoked Potentials, Auditory, Brainstem
          Cervical Vertebrae
          Treatment Outcomes
          Human
          Female
          Adult
          Middle Age
          Randomized Controlled Trials
          Random Assignment
          Combined Modality Therapy
          Neural Transmission
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: Migraine is an important disease due to its impact on global health. Due to association of neck pain with migraine, manual therapy (MT) often used in management. The aim of this study was to evaluate the effects of upper cervical spine MT on specific mechanisms including central sensitization (CS) and brainstem auditory evoked potentials (BAEPs) in subjects with migraine and neck pain. 30 subjects with migraine and neck pain (30 female, mean age 43.10 ± 8.13) were randomly assigned to a medication plus MT (MedMT) group, a medication plus sham manual therapy (sham MT) group, and a medication alone (Med) group. CS was evaluated using the Central Sensitization Inventory (CSI) and BAEP determined electrophysiologically in all subjects pre and post intervention. Subjects in MedMT and sham MT groups received either 4 sessions of MT or sham MT. All subjects received medication. Subjects in MedMT group had a significant reduction in CSI score (P < 0.05) compare to the other 2 groups. For BAEPs, MedMT and sham MT groups had significantly decreased wave V latency on the right side (P < 0.05) compared to Med group. Manual therapy plus medication may have beneficial effects in people with migraine and neck pain by normalizing central sensitization levels. Additionally, upper cervical manual therapy or sham manual therapy have demonstrable neurophysiological effects reflected by changes in the auditory transmission pathways in the brainstem. Further research is required to investigate the mechanisms of action of MT in migraine.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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