Local wound care management for pyoderma gangrenosum.

Pyoderma gangrenosum (PG) is a rare, painful neutrophilic dermatosis characterized by rapidly progressing skin ulcers. Despite the importance of local wound care in managing PG, there is no consensus or evidence‐based guidelines. This systematic review aimed to investigate local wound care strategie...

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Publicado en:International Wound Journal Vol. 21; no. 11; pp. 1 - 4
Autores principales: Haroon, Adeeb, Gillespie, Jordan, Roland‐McGowan, Jaclyn, Seervai, Riyad N. H., Gould, Lisa J., Dini, Valentina, Ortega‐Loayza, Alex G.
Formato: letter research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2024
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Wound Journal
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      dt: Nov2024
      vid: 21
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/iwj.70135
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        atl: Local wound care management for pyoderma gangrenosum.
      aug:
        au:
          Haroon, Adeeb
          Gillespie, Jordan
          Roland‐McGowan, Jaclyn
          Seervai, Riyad N. H.
          Gould, Lisa J.
          Dini, Valentina
          Ortega‐Loayza, Alex G.
        affil: Department of Dermatology, Oregon Health and Science University, Portland Oregon,, USA
      sug:
        subj:
          Wound Care
          Pyoderma Gangrenosum Therapy
          Human
          Embase
          Medline
          Cochrane Library
          Debridement Methods
          Adrenal Cortex Hormones Therapeutic Use
          Bandages and Dressings
          Wound Healing
          Superinfection
          Funding Source
      ab: Pyoderma gangrenosum (PG) is a rare, painful neutrophilic dermatosis characterized by rapidly progressing skin ulcers. Despite the importance of local wound care in managing PG, there is no consensus or evidence‐based guidelines. This systematic review aimed to investigate local wound care strategies for PG. A comprehensive search of Embase, MEDLINE, and the Cochrane Library yielded 1213 references, from which 269 studies were included, covering 351 patients. The most reported treatment methods included sharp debridement (11%), topical corticosteroids (27%) and non‐adherent dressings (12%). However, no clear correlation between these treatments and healing outcomes was found likely due to confounding factors such as varied wound sizes, superinfection and inconsistent reporting. Additionally, directed wound care regimens have not been able to show statistical significance for healing outcomes. Our study describes the current local wound care landscape and underscores a critical gap in the current literature regarding standardized treatment protocols for PG.
      pubtype: Academic Journal
      doctype:
        letter
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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