The Role of Global Longitudinal Strain in Predicting Left Ventricular Reverse Remodeling After Mitral Valve Replacement Surgery in Patients With Primary Mitral Regurgitation.

Objectives: This study aimed to identify the utility of global longitudinal strain (GLS) as a reliable parameter that can accurately forecast left ventricle reverse remodeling (LVRR) in patients undergoing valve replacement surgery for severe chronic primary mitral regurgitation (MR), thereby aiding...

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Published in:Echocardiography Vol. 41; no. 11; pp. 1 - 9
Main Authors: Natalino, Liem Audi, Marsam, Real Kusumanjaya, Dinarti, Lucia Kris, Mumpuni, Hasanah, Anggrahini, Dyah Wulan
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Nov2024
Online Access:View this record in EBSCOhost
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      dt: Nov2024
      vid: 41
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.15950
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        atl: The Role of Global Longitudinal Strain in Predicting Left Ventricular Reverse Remodeling After Mitral Valve Replacement Surgery in Patients With Primary Mitral Regurgitation.
      aug:
        au:
          Natalino, Liem Audi
          Marsam, Real Kusumanjaya
          Dinarti, Lucia Kris
          Mumpuni, Hasanah
          Anggrahini, Dyah Wulan
        affil: Division of Cardiology and Vascular Medicine, National Hospital Surabaya, Wiyung, Indonesia
      sug:
        subj:
          Mitral Valve Insufficiency Surgery
          Heart Valve Prosthesis
          Ventricular Remodeling
          Forecasting
          Global Longitudinal Strain
          Predictive Value of Tests Evaluation
          Mitral Valve Insufficiency Mortality
          Risk Assessment
          Human
          Adolescence
          Adult
          Middle Age
          Aged
          Retrospective Design
          Record Review
          Nonexperimental Studies
          Echocardiography
          Heart Ventricle, Left Physiology
          Severity of Illness
          Descriptive Statistics
          Bivariate Statistics
          Multivariate Analysis
          Sensitivity and Specificity
          Odds Ratio
          Confidence Intervals
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
      ab: Objectives: This study aimed to identify the utility of global longitudinal strain (GLS) as a reliable parameter that can accurately forecast left ventricle reverse remodeling (LVRR) in patients undergoing valve replacement surgery for severe chronic primary mitral regurgitation (MR), thereby aiding in assessing mortality and morbidity risk. Methods: This retrospective observational study involved severe primary MR patients who underwent valve replacement surgery between 2018 and 2023. Pre‐ and postsurgery echocardiography data were collected, with GLS measurements utilized to assess left ventricular function. Various echocardiography parameters, including MR severity and LV dimensions, were analyzed. Bivariate and multivariate analyses were performed to explore relationships between GLS and LVRR. Results: This study enrolled 103 patients (54.4% male; mean age 45.4 ± 13.6 years). Statistical analyses revealed GLS to be an independent predictor of LVRR, with a threshold of −16.25% showing 89% sensitivity and 50% specificity. Each 1% increase in GLS corresponded to a 1.14‐fold (odds ratio [OR]: 1.14; 95% confidence interval [CI]: 1.01–1.31; p < 0.05) increased likelihood of LVRR. Conclusion: These findings highlight GLS's potential as a prognostic marker for postsurgical outcomes in severe MR patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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