Early Detection of Left Ventricular Dysfunction With Machine Learning‐Based Strain Imaging in Aortic Stenosis Patients.

Purpose: Aortic stenosis (AS) is a common cardiovascular condition where early detection of left ventricular (LV) dysfunction is essential for timely intervention and optimal management. Current echocardiographic measurements, such as ejection fraction (EF), are insensitive to minor changes in LV fu...

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Publicado en:Echocardiography Vol. 41; no. 11; pp. 1 - 17
Autores principales: Yahav, Amir, Adam, Dan
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2024
      vid: 41
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.70007
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        atl: Early Detection of Left Ventricular Dysfunction With Machine Learning‐Based Strain Imaging in Aortic Stenosis Patients.
      aug:
        au:
          Yahav, Amir
          Adam, Dan
        affil: Faculty of Biomedical Engineering, Technion – Israel Institute of Technology, Haifa, Israel
      sug:
        subj:
          Ventricular Dysfunction, Left Diagnosis
          Early Diagnosis
          Machine Learning Algorithms
          Diagnosis, Computer Assisted
          Aortic Valve Stenosis
          Human
          Female
          Male
          Cardiac Patients
          Machine Learning
          Echocardiography
          Quality Assurance
          Decision Trees
          Chest Pain
          ROC Curve
          Descriptive Statistics
          Funding Source
          Female
          Male
      ab: Purpose: Aortic stenosis (AS) is a common cardiovascular condition where early detection of left ventricular (LV) dysfunction is essential for timely intervention and optimal management. Current echocardiographic measurements, such as ejection fraction (EF), are insensitive to minor changes in LV function, and strain imaging is typically limited to the global longitudinal strain (GLS) parameter due to robustness issues. This study introduces a novel, fully automatic algorithm to enhance the detection of LV dysfunction in AS patients using multiple strain imaging parameters. Methods: We applied supervised machine‐learning techniques to classify data from 82 severe AS patients, 96 chest pain subjects, and 319 healthy volunteers. Results: Our model significantly outperformed EF and GLS in distinguishing AS patients from healthy volunteers (area under the curve [AUC] = 0.97 vs. 0.88 and 0.82, respectively). It also surpassed EF and GLS in differentiating AS patients from chest pain subjects (AUC = 0.95 vs. 0.90 and 0.55, respectively). Conclusion: This novel, clinically interpretable model leverages the potential of strain imaging to enhance diagnostic accuracy and guide clinical decision‐making in LV dysfunction, thereby improving clinical practice.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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