Effects of chronic betaine supplementation on exercise performance: Systematic review and meta-analysis.

Betaine supplementation, a dietary practice that possesses potential effects on exercise performance, has undergone extensive study. This study aimed to systematically review and meta-analyse betaine supplementation's effects on exercise performance. We searched PubMed, Web of Science, Scopus, and G...

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Publicado en:Journal of Sports Sciences Vol. 42; no. 22; pp. 2131 - 2145
Autores principales: Zawieja, Emilia, Machek, Steven, Zanchi, Nelo Eidy, Cholewa, Jason, Woźniewicz, Małgorzata
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Nov2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2024
      vid: 42
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/02640414.2024.2423578
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        atl: Effects of chronic betaine supplementation on exercise performance: Systematic review and meta-analysis.
      aug:
        au:
          Zawieja, Emilia
          Machek, Steven
          Zanchi, Nelo Eidy
          Cholewa, Jason
          Woźniewicz, Małgorzata
        affil: Department of Human Nutrition and Dietetics, Poznań University of Life Sciences, Poznań, Poland
      sug:
        subj:
          Dietary Supplementation
          Betaine Pharmacodynamics
          Exercise Physiology Drug Effects
          Task Performance and Analysis
          Human
          Systematic Review
          Meta Analysis
          PubMed
          Adolescence
          Adult
          Middle Age
          Checklists
          Qualitative Studies
          Descriptive Statistics
          Confidence Intervals
          Isometric Exercises
          Physical Endurance Drug Effects
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
      ab: Betaine supplementation, a dietary practice that possesses potential effects on exercise performance, has undergone extensive study. This study aimed to systematically review and meta-analyse betaine supplementation's effects on exercise performance. We searched PubMed, Web of Science, Scopus, and Google Scholar, focusing on studies comparing chronic betaine to a placebo in healthy humans aged 15–60 years, measuring exercise outcomes. Studies with acute betaine supplementation, no control group, or animals were excluded. Quality assessment was done using the Cochrane Risk of Bias Tool, and a random-effects model was employed for the meta-analysis. The review included 17 studies with 317 participants (21% female). The results revealed a significant effect size of 0.47 (95% CI 0.04 to 0.89) for maximal strength (1RM, 3RM, maximal isokinetic or isometric force), particularly in the lower body (SMD: 0.49, 95% CI 0.01 to 0.98). No significant effects were found for upper body strength, cycling sprint power, bench press throws power, or muscular endurance. However, vertical jumping performance improved significantly (SMD: 0.36, 95% CI 0.03 to 0.69) after excluding a low-quality study. In conclusion, betaine supplementation for at least 7 days significantly enhances muscular strength, especially lower body strength, and shows potential in improving vertical jumping performance.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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