Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies.
Acute myeloid leukemia (AML) is a heterogeneous blood-related neoplasm that predominantly afflicts older adults with a poor prognosis due to their physical condition and the presence of medical accompanying comorbidities, adverse biological disease features, and suitability for induction intensive c...
| Publicado en: | Current Oncology Vol. 31; no. 11; pp. 6632 - 6659 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
MDPI
Nov2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181170851&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181170851 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11980052 5EKK jtl: Current Oncology issn: 11980052 maglogo: N pubinfo: dt: Nov2024 vid: 31 iid: 11 pid: 97109 pub: MDPI artinfo: ui: 181170851 10.3390/curroncol31110490 181170851 ppf: 6632 ppct: 27 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies. aug: au: Niscola, Pasquale Gianfelici, Valentina Catalano, Gianfranco Giovannini, Marco Mazzone, Carla Noguera, Nelida Ines de Fabritiis, Paolo affil: Hematology Unit, S. Eugenio Hospital (ASL Roma 2), 00144 Rome, Italy sug: ab: Acute myeloid leukemia (AML) is a heterogeneous blood-related neoplasm that predominantly afflicts older adults with a poor prognosis due to their physical condition and the presence of medical accompanying comorbidities, adverse biological disease features, and suitability for induction intensive chemotherapy and allogenic stem cells transplantation. Recent research into the molecular and biological factors contributing to disease development and progression has led to significant advancements in treatment approaches for older patients with AML. This review article discusses the latest biological and therapeutic developments that are transforming the management of AML in older adults. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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