Advanced Magnetic Resonance Imaging for Detection of Liver Fibrosis and Inflammation in Autoimmune Hepatitis: A State-of-the-Art Review.
Autoimmune hepatitis is a rare chronic liver disease, associated with a high level of morbidity and high mortality; approximately 40% of patients with severe untreated disease die within 6 months of diagnosis. It should be treated to achieve complete biochemical and histologic resolution of the dise...
| Publicado en: | Seminars in Ultrasound, CT & MRI Vol. 45; no. 6; pp. 464 - 476 |
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| Autores principales: | , , , |
| Formato: | review Journal Article |
| Publicado: |
Elsevier B.V.
Dec2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181410020&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181410020 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08872171 4H1 jtl: Seminars in Ultrasound, CT & MRI issn: 08872171 maglogo: N pubinfo: dt: Dec2024 vid: 45 iid: 6 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 181410020 181410020 181410020 10.1053/j.sult.2024.07.010 181410020 ppf: 464 ppct: 12 formats: tig: atl: Advanced Magnetic Resonance Imaging for Detection of Liver Fibrosis and Inflammation in Autoimmune Hepatitis: A State-of-the-Art Review. aug: au: Gomes, Natália B.N. Torres, Ulysses S. Ferraz, Maria Lucia C.G. D'Ippolito, Giuseppe affil: Department of Radiology, Grupo Fleury, São Paulo, São Paulo, Brazil sug: subj: Hepatitis, Autoimmune Complications Liver Cirrhosis Diagnosis Biological Markers Magnetic Resonance Imaging Chronic Disease Mortality Hepatitis, Autoimmune Mortality Morbidity Chronic Disease Prevention and Control Hepatitis, Autoimmune Prevention and Control Adrenal Cortex Hormones Therapeutic Use Disease Progression Prevention and Control Biopsy Disease Remission Immunosuppression Health Care Costs Diagnostic Errors ab: Autoimmune hepatitis is a rare chronic liver disease, associated with a high level of morbidity and high mortality; approximately 40% of patients with severe untreated disease die within 6 months of diagnosis. It should be treated to achieve complete biochemical and histologic resolution of the disease using corticosteroids and immunosuppression to prevent further progression to cirrhosis. The use of invasive liver biopsy is recommended for the staging and assessment of inflammation and fibrosis for treatment decision-making in the face of an unsatisfactory response or clinical remission, including being a determinant for withdrawal of immunosuppression. On the other hand, liver biopsy is invasive, costly, and not free of complications. It also has potential sampling error and poor interobserver agreement. The limitations of liver biopsy highlight the importance of developing new imaging biomarkers that allow accurate and non-invasive assessment of autoimmune hepatitis in terms of liver inflammation and fibrosis, developing the virtual biopsy concept. Therefore, we review the state-of-the-art of Magnetic Resonance Imaging sequences for the noninvasive evaluation of autoimmune hepatitis, including historical advances and future directions. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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