Changes in the epidemiology and antimicrobial resistance patterns of Streptococcus pneumoniae from pediatric community acquired pneumonia patients attended in a Chinese hospital during the COVID-19 pandemic.
Purpose: The COVID-19 pandemic has altered the infection dynamics of numerous pathogens. This study aimed to elucidate its impact on Streptococcus pneumoniae (S. pneumoniae) infections in children with community acquired pneumonia (CAP). Methods: A retrospective analysis was conducted in pediatric C...
| Publicado en: | Infection Vol. 52; no. 6; pp. 2455 - 2465 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181463213&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181463213 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03008126 NXO jtl: Infection issn: 03008126 maglogo: N pubinfo: dt: Dec2024 vid: 52 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 181463213 177697365 181463213 181463213 10.1007/s15010-024-02308-8 181463213 ppf: 2455 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Changes in the epidemiology and antimicrobial resistance patterns of Streptococcus pneumoniae from pediatric community acquired pneumonia patients attended in a Chinese hospital during the COVID-19 pandemic. aug: au: Ai, Ling Zhou, Chanjuan Fang, Liang Liu, Beizhong Gong, Fang affil: https://ror.org/017z00e58 Department of General Practice, Yongchuan Hospital of Chongqing Medical University, No. 439, Xuanhua Street, 402160, Chongqing, China sug: subj: Streptococcal Infections Pathology Streptococcal Infections Pathology Pneumonia, Bacterial Risk Factors Pneumonia, Bacterial Epidemiology Community-Acquired Infections Epidemiology Antibiotics Therapeutic Use Drug Resistance, Microbial In Infancy and Childhood Pneumonia, Bacterial Drug Therapy Treatment Outcomes Human Pneumonia, Bacterial Diagnosis Retrospective Design China Infant Child, Preschool Child Adolescence Infant: 1-23 months Child, Preschool: 2-5 years Child: 6-12 years Adolescent: 13-18 years ab: Purpose: The COVID-19 pandemic has altered the infection dynamics of numerous pathogens. This study aimed to elucidate its impact on Streptococcus pneumoniae (S. pneumoniae) infections in children with community acquired pneumonia (CAP). Methods: A retrospective analysis was conducted in pediatric CAP patients admitted before (2018–2019) and during (2020–2022) the COVID-19 pandemic. The epidemiology and antimicrobial resistance (AMR) patterns of S. pneumoniae were compared to reveal the impact of the pandemic. Results: A total of 968 S. pneumoniae-associated pediatric CAP patients were enrolled. Although the positivity rate and gender of patients were stable across both periods, the age notably increased in 2021 and 2022. Additionally, significant changes were observed in the co-infections with several pathogens and the resistance rates to certain antibiotics during the COVID-19 pandemic. The resistance rate to clindamycin and quinupristin-dalfopristin increased, whereas the resistance rate to tetracycline, trimethoprim-sulfamethoxazole, telithromycin, and proportion of multi-drug resistant isolates decreased. The number of S. pneumoniae strains and resistant isolates exhibited similar seasonal patterns in 2018 and 2019, peaking in November or December with another minor peak in March or April. During the COVID-19 pandemic, there was a sharp decrease in February 2020 and no resurgence was observed at the end of 2022. Additionally, the minor peak was absent in 2020 and shifted to other months in 2021 and 2022. Conclusions: The COVID-19 pandemic has markedly altered the infection spectrum of S. pneumoniae in pediatric CAP patients, as evidenced by shifts in the age of patients, respiratory co-infections, AMR patterns, and seasonal trends. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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