Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions.

Objective To analyze the prognosis and risk factors of the anterior and posterior circulation tandem lesions (TLs) patients after recanalization treatment. Methods The general and clinical data of 42 patients with TLs who received recanalization treatment in Shijiazhuang People's Hospital from April...

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Publicado en:Chinese Journal of Contemporary Neurology & Neurosurgery Vol. 24; no. 11; pp. 927 - 933
Autores principales: YANG Lei, HAN Yong-feng, ZHANG Dong-liang, SU Xian-hui, JIN Wen-cai, ZHANG Xue-jing
Formato: research tables/charts Journal Article
Publicado: Chinese Journal of Contemporary Neurology & Neurosurgery Nov2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2024
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      pub: Chinese Journal of Contemporary Neurology & Neurosurgery
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        10.3969/j.issn.1672-6731.2024.11.009
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        atl: Analysis of risk factors of poor prognosis after recanalization treatment of anterior and posterior circulation tandem lesions.
      aug:
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          YANG Lei
          HAN Yong-feng
          ZHANG Dong-liang
          SU Xian-hui
          JIN Wen-cai
          ZHANG Xue-jing
        affil: Department of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei, China
      sug:
        subj:
          Ischemic Stroke Surgery
          Ischemic Stroke Prognosis
          Thrombectomy
          Postoperative Complications Risk Factors
          Human
          China
          Retrospective Design
          Record Review
          Step-Wise Multiple Regression
          Endovascular Procedures
          Descriptive Statistics
          Chi Square Test
          Odds Ratio
          Confidence Intervals
          Severity of Illness
          NIH Stroke Scale
          Scales
      ab: Objective To analyze the prognosis and risk factors of the anterior and posterior circulation tandem lesions (TLs) patients after recanalization treatment. Methods The general and clinical data of 42 patients with TLs who received recanalization treatment in Shijiazhuang People's Hospital from April 2019 to August 2022 were retrospectively collected. The prognosis of 90 d after surgery was evaluated by the modified Rankin Scale (mRS). Univariate and multivariate stepwise Logistic regression analyses were used to investigated the risk factors of poor prognosis of TLs. Results According to mRS scores at the 90 d after surgery, the patients were divided into good prognosis group (mRS ≤ 2, n = 21) and poor prognosis group (mRS > 2, n = 21). The National Institutes of Health Stroke Scale (NIHSS) score at admission (Z = - 2.916, P = 0.004), time from onset to recanalization (Z = - 2.048, P = 0.041), mechanical thrombectomy times ≥ 3 (χ² = 4.725, P = 0.030) and the proportion of hematoma type hemorrhagic transformation (χ² = 8.400, P = 0.004) in the poor prognosis group were higher than those in good prognosis group. Logistic regression analysis showed that high NIHSS score at admission (OR = 12.457, 95%CI: 2.066-75.120; P = 0.006), mechanical thrombectomy times ≥ 3 (OR = 9.387, 95%CI: 1.222-72.140; P = 0.031) and postoperative hemorrhagic transformation (OR = 7.237, 95%CI: 1.019-51.403; P = 0.048) were risk factors of poor prognosis of TLs. Conclusions Anterior and posterior circulation TLs patients with lower NHISS score at admission, mechanical thrombectomy times < 3 and without postoperative hemorrhagic transformation may have good prognosis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Chinese
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