Long-term prognosis of endovascular treatment in patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window.
Objective To evaluate the long-term prognosis in patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window (> 24 h) who received endovascular treatment (EVT) combined with best medical treatment (BMT), compared to those treated with BMT alone. M...
| Publicado en: | Chinese Journal of Contemporary Neurology & Neurosurgery Vol. 24; no. 11; pp. 933 - 943 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Chinese Journal of Contemporary Neurology & Neurosurgery
Nov2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181466929&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181466929 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16726731 FDQ6 jtl: Chinese Journal of Contemporary Neurology & Neurosurgery issn: 16726731 maglogo: N pubinfo: dt: Nov2024 vid: 24 iid: 11 pid: 80951 pub: Chinese Journal of Contemporary Neurology & Neurosurgery artinfo: ui: 181466929 181466929 181466929 10.3969/j.issn.1672-6731.2024.11.010 181466929 ppf: 933 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Long-term prognosis of endovascular treatment in patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window. aug: au: LIU Shu-ling XU Yong-bo LI Yang WANG Si-fei LUO Lei-lei WEI Ming affil: Department of Neurosurgery, Tianjin Huanhu Hospital; Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin 300350, China sug: subj: Ischemic Stroke Prognosis Arterial Occlusive Diseases Therapy Endovascular Procedures Risk Assessment Human Prospective Studies China Univariate Statistics Multivariate Analysis Logistic Regression Sensitivity and Specificity Probability Age Factors Hypertension Risk Factors Odds Ratio Descriptive Statistics Confidence Intervals Scales ab: Objective To evaluate the long-term prognosis in patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window (> 24 h) who received endovascular treatment (EVT) combined with best medical treatment (BMT), compared to those treated with BMT alone. Methods This study included 158 patients from a prospective cohort of acute ischemic stroke due to large vessel occlusion were conducted at Tianjin Huanhu Hospital from November 2021 to July 2023. The 158 patients with anterior circulation large vessel occlusion were divided into received EVT combined with BMT (EVT group, n = 70) and received BMT alone (BMT group, n = 88). Long - term neurological prognosis was assessed using the modified Rankin Scale (mRS) 12 months after onset. Univariate and multivariate stepwise Logistic regression analyses were useded to investigated the risk factors of long-term neurological prognosis. Sensitivity analyses were performed using propensity score matching (PSM) and multiple imputation (MI). Results Logistic regression analysis showed that EVT was a protective factor for good long-term neurological prognosis (mRS score ≤ 2; OR = 3.110, 95%CI: 1.460-6.620, P = 0.003), increasing age (OR = 0.955, 95%CI: 0.924-0.987; P = 0.007) and hypertension (OR = 0.418, 95%CI: 0.187-0.936; P = 0.034) were risk factors. In the sensitivity analyses of the primary outcome, both the PSM and MI datasets showed that the proportion of patients with a good long-term neurological prognosis was significantly higher in the EVT group compared to the BMT group (PSM: aOR = 3.610, 95%CI: 1.370-9.550, P = 0.010; MI: aOR = 3.870, 95%CI: 1.780-8.440, P = 0.000). The results were consistent with the main analysis. Conclusions Compared to BMT group, EVT group patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window was demonstrated a significantly better long-term neurological prognosis. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: Chinese refInfo: holdings: @attributes: islocal: N |
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