Differential Diagnosis of Diabetic Foot Osteomyelitis and Charcot Neuropathic Osteoarthropathy with Deep Learning Methods.

Our study aims to evaluate the potential of a deep learning (DL) algorithm for differentiating the signal intensity of bone marrow between osteomyelitis (OM), Charcot neuropathic osteoarthropathy (CNO), and trauma (TR). The local ethics committee approved this retrospective study. From 148 patients,...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 5; pp. 2454 - 2466
Autores principales: Cakir, Maide, Tulum, Gökalp, Cuce, Ferhat, Yilmaz, Kerim Bora, Aralasmak, Ayse, Isik, Muhammet İkbal, Canbolat, Hüseyin
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01067-0
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        atl: Differential Diagnosis of Diabetic Foot Osteomyelitis and Charcot Neuropathic Osteoarthropathy with Deep Learning Methods.
      aug:
        au:
          Cakir, Maide
          Tulum, Gökalp
          Cuce, Ferhat
          Yilmaz, Kerim Bora
          Aralasmak, Ayse
          Isik, Muhammet İkbal
          Canbolat, Hüseyin
        affil: https://ror.org/02mtr7g38 Department of Electrical Engineering, Faculty of Engineering and Natural Sciences, Bandirma Onyedi Eylul University, Balikesir, Turkey
      sug:
        subj:
          Diabetic Foot Diagnosis
          Osteomyelitis Diagnosis
          Arthropathy, Neurogenic Diagnosis
          Diagnosis, Differential
          Deep Learning Methods
          Algorithms Utilization
          Trauma Diagnosis
          Sensitivity and Specificity
          Human
          Retrospective Design
          Descriptive Statistics
          Record Review
          Image Interpretation, Computer Assisted
      ab: Our study aims to evaluate the potential of a deep learning (DL) algorithm for differentiating the signal intensity of bone marrow between osteomyelitis (OM), Charcot neuropathic osteoarthropathy (CNO), and trauma (TR). The local ethics committee approved this retrospective study. From 148 patients, segmentation resulted in 679 labeled regions for T1-weighted images (comprising 151 CNO, 257 OM, and 271 TR) and 714 labeled regions for T2-weighted images (consisting of 160 CNO, 272 OM, and 282 TR). We employed both multi-class classification (MCC) and binary-class classification (BCC) approaches to compare the classification outcomes of CNO, TR, and OM. The ResNet-50 and the EfficientNet-b0 accuracy values were computed at 96.2% and 97.1%, respectively, for T1-weighted images. Additionally, accuracy values for ResNet-50 and the EfficientNet-b0 were determined at 95.6% and 96.8%, respectively, for T2-weighted images. Also, according to BCC for CNO, OM, and TR, the sensitivity of ResNet-50 is 91.1%, 92.4%, and 96.6% and the sensitivity of EfficientNet-b0 is 93.2%, 97.6%, and 98.1% for T1, respectively. For CNO, OM, and TR, the sensitivity of ResNet-50 is 94.9%, 83.6%, and 97.9% and the sensitivity of EfficientNet-b0 is 95.6%, 85.2%, and 98.6% for T2, respectively. The specificity values of ResNet-50 for CNO, OM, and TR in T1-weighted images are 98.1%, 97.9%, and 94.7% and 98.6%, 97.5%, and 96.7% in T2-weighted images respectively. Similarly, for EfficientNet-b0, the specificity values are 98.9%, 98.7%, and 98.4% and 99.1%, 98.5%, and 98.7% for T1-weighted and T2-weighted images respectively. In the diabetic foot, deep learning methods serve as a non-invasive tool to differentiate CNO, OM, and TR with high accuracy.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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