Deep Convolutional Neural Network for Dedicated Regions-of-Interest Based Multi-Parameter Quantitative Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of the Knee Joint.

We proposed an end-to-end deep learning convolutional neural network (DCNN) for region-of-interest based multi-parameter quantification (RMQ-Net) to accelerate quantitative ultrashort echo time (UTE) MRI of the knee joint with automatic multi-tissue segmentation and relaxometry mapping. The study in...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 5; pp. 2126 - 2135
Autores principales: Lu, Xing, Ma, Yajun, Chang, Eric Y., Athertya, Jiyo, Jang, Hyungseok, Jerban, Saeed, Covey, Dana C., Bukata, Susan, Chung, Christine B., Du, Jiang
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01089-8
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        atl: Deep Convolutional Neural Network for Dedicated Regions-of-Interest Based Multi-Parameter Quantitative Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of the Knee Joint.
      aug:
        au:
          Lu, Xing
          Ma, Yajun
          Chang, Eric Y.
          Athertya, Jiyo
          Jang, Hyungseok
          Jerban, Saeed
          Covey, Dana C.
          Bukata, Susan
          Chung, Christine B.
          Du, Jiang
        affil: Department of Radiology, University of California, 9452 Medical Center Dr, 92037, San Diego, San Diego, CA, USA
      sug:
        subj:
          Magnetic Resonance Imaging
          Deep Learning
          Osteoarthritis, Knee Diagnosis
          Neural Networks (Computer)
          Diagnosis, Computer Assisted
          Cartilage Pathology
          Algorithms
          Knee Joint Physiopathology
          Human
          Quantitative Studies
          Descriptive Statistics
          Prediction Models
          Pearson's Correlation Coefficient
          Funding Source
      ab: We proposed an end-to-end deep learning convolutional neural network (DCNN) for region-of-interest based multi-parameter quantification (RMQ-Net) to accelerate quantitative ultrashort echo time (UTE) MRI of the knee joint with automatic multi-tissue segmentation and relaxometry mapping. The study involved UTE-based T1 (UTE-T1) and Adiabatic T1ρ (UTE-AdiabT1ρ) mapping of the knee joint of 65 human subjects, including 20 normal controls, 29 with doubtful-minimal osteoarthritis (OA), and 16 with moderate-severe OA. Comparison studies were performed on UTE-T1 and UTE-AdiabT1ρ measurements using 100%, 43%, 26%, and 18% UTE MRI data as the inputs and the effects on the prediction quality of the RMQ-Net. The RMQ-net was modified and retrained accordingly with different combinations of inputs. Both ROI-based and voxel-based Pearson correlation analyses were performed. High Pearson correlation coefficients were achieved between the RMQ-Net predicted UTE-T1 and UTE-AdiabT1ρ results and the ground truth for segmented cartilage with acceleration factors ranging from 2.3 to 5.7. With an acceleration factor of 5.7, the Pearson r-value achieved 0.908 (ROI-based) and 0.945 (voxel-based) for UTE-T1, and 0.733 (ROI-based) and 0.895 (voxel-based) for UTE-AdiabT1ρ, correspondingly. The results demonstrated that RMQ-net can significantly accelerate quantitative UTE imaging with automated segmentation of articular cartilage in the knee joint.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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