Development of a Secure Web-Based Medical Imaging Analysis Platform: The AWESOMME Project.

Precision medicine research benefits from machine learning in the creation of robust models adapted to the processing of patient data. This applies both to pathology identification in images, i.e., annotation or segmentation, and to computer-aided diagnostic for classification or prediction. It come...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 5; pp. 2612 - 2627
Autores principales: Diot-Dejonghe, Tiphaine, Leporq, Benjamin, Bouhamama, Amine, Ratiney, Helene, Pilleul, Frank, Beuf, Olivier, Cervenansky, Frederic
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
      vid: 37
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01110-0
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        atl: Development of a Secure Web-Based Medical Imaging Analysis Platform: The AWESOMME Project.
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          Diot-Dejonghe, Tiphaine
          Leporq, Benjamin
          Bouhamama, Amine
          Ratiney, Helene
          Pilleul, Frank
          Beuf, Olivier
          Cervenansky, Frederic
        affil: INSA-Lyon, Université Claude Bernard Lyon 1, CNRS, Inserm, CREATIS UMR 5220, U1294, F-69XXX, Lyon, France
      sug:
        subj:
          Osteosarcoma Therapy
          Treatment Outcomes Evaluation
          Diagnostic Imaging Methods
          Image Interpretation, Computer Assisted
          Software Design
          Deep Learning
          Radiomics
          Human
          Medical Informatics
          Machine Learning
          Monitoring, Physiologic
          Internet
          Data Security
          Access to Information
          Individualized Medicine
          Funding Source
      ab: Precision medicine research benefits from machine learning in the creation of robust models adapted to the processing of patient data. This applies both to pathology identification in images, i.e., annotation or segmentation, and to computer-aided diagnostic for classification or prediction. It comes with the strong need to exploit and visualize large volumes of images and associated medical data. The work carried out in this paper follows on from a main case study piloted in a cancer center. It proposes an analysis pipeline for patients with osteosarcoma through segmentation, feature extraction and application of a deep learning model to predict response to treatment. The main aim of the AWESOMME project is to leverage this work and implement the pipeline on an easy-to-access, secure web platform. The proposed WEB application is based on a three-component architecture: a data server, a heavy computation and authentication server and a medical imaging web-framework with a user interface. These existing components have been enhanced to meet the needs of security and traceability for the continuous production of expert data. It innovates by covering all steps of medical imaging processing (visualization and segmentation, feature extraction and aided diagnostic) and enables the test and use of machine learning models. The infrastructure is operational, deployed in internal production and is currently being installed in the hospital environment. The extension of the case study and user feedback enabled us to fine-tune functionalities and proved that AWESOMME is a modular solution capable to analyze medical data and share research algorithms with in-house clinicians.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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