Synthetic Low-Energy Monochromatic Image Generation in Single-Energy Computed Tomography System Using a Transformer-Based Deep Learning Model.

While dual-energy computed tomography (DECT) technology introduces energy-specific information in clinical practice, single-energy CT (SECT) is predominantly used, limiting the number of people who can benefit from DECT. This study proposed a novel method to generate synthetic low-energy virtual mon...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 5; pp. 2688 - 2698
Autores principales: Koike, Yuhei, Ohira, Shingo, Kihara, Sayaka, Anetai, Yusuke, Takegawa, Hideki, Nakamura, Satoaki, Miyazaki, Masayoshi, Konishi, Koji, Tanigawa, Noboru
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Oct2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2024
      vid: 37
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01111-z
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        atl: Synthetic Low-Energy Monochromatic Image Generation in Single-Energy Computed Tomography System Using a Transformer-Based Deep Learning Model.
      aug:
        au:
          Koike, Yuhei
          Ohira, Shingo
          Kihara, Sayaka
          Anetai, Yusuke
          Takegawa, Hideki
          Nakamura, Satoaki
          Miyazaki, Masayoshi
          Konishi, Koji
          Tanigawa, Noboru
        affil: https://ror.org/001xjdh50 Department of Radiology, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata, Osaka, Japan
      sug:
        subj:
          Tomography, X-Ray Computed Methods
          Deep Learning
          Convolutional Neural Networks
          Image Processing, Computer Assisted
          Technology, Radiologic
          Human
          Comparative Studies
          Record Review
          Retrospective Design
          Descriptive Statistics
          Data Analysis Software
          Head and Neck Neoplasms Radiotherapy
          Head and Neck Neoplasms Radiography
          Artificial Intelligence, Generative
          Radiographic Image Enhancement
          Quality Improvement
          Cancer Patients
          Inpatients
          Image Retrieval
          Picture Archiving and Communication Systems
          Radiographic Image Interpretation, Computer-Assisted
          Funding Source
      ab: While dual-energy computed tomography (DECT) technology introduces energy-specific information in clinical practice, single-energy CT (SECT) is predominantly used, limiting the number of people who can benefit from DECT. This study proposed a novel method to generate synthetic low-energy virtual monochromatic images at 50 keV (sVMI50keV) from SECT images using a transformer-based deep learning model, SwinUNETR. Data were obtained from 85 patients who underwent head and neck radiotherapy. Among these, the model was built using data from 70 patients for whom only DECT images were available. The remaining 15 patients, for whom both DECT and SECT images were available, were used to predict from the actual SECT images. We used the SwinUNETR model to generate sVMI50keV. The image quality was evaluated, and the results were compared with those of the convolutional neural network-based model, Unet. The mean absolute errors from the true VMI50keV were 36.5 ± 4.9 and 33.0 ± 4.4 Hounsfield units for Unet and SwinUNETR, respectively. SwinUNETR yielded smaller errors in tissue attenuation values compared with those of Unet. The contrast changes in sVMI50keV generated by SwinUNETR from SECT were closer to those of DECT-derived VMI50keV than the contrast changes in Unet-generated sVMI50keV. This study demonstrated the potential of transformer-based models for generating synthetic low-energy VMIs from SECT images, thereby improving the image quality of head and neck cancer imaging. It provides a practical and feasible solution to obtain low-energy VMIs from SECT data that can benefit a large number of facilities and patients without access to DECT technology.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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