Alteration in EEG Delta and Beta Power During Working Memory Performance Differentiates Patients with Parkinson's Disease with and without Dementia.
Background and Objectives: Working memory (WM) impairment is a common and progressive abnormality in Parkinson's disease (PD), which ultimately leads to dementia. Individuals with PD exhibit altered electroencephalogram (EEG) patterns while engaging in tasks that require WM. The study examined the E...
| Publicado en: | Annals of Indian Academy of Neurology Vol. 27; no. 6; pp. 663 - 668 |
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| Autores principales: | , , |
| Formato: | diagnostic images research Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Nov/Dec2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181811511&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181811511 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09722327 259F jtl: Annals of Indian Academy of Neurology issn: 09722327 maglogo: N pubinfo: dt: Nov/Dec2024 vid: 27 iid: 6 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 181811511 181811511 181811511 10.4103/aian.aian_198_24 181811511 ppf: 663 ppct: 5 formats: tig: atl: Alteration in EEG Delta and Beta Power During Working Memory Performance Differentiates Patients with Parkinson's Disease with and without Dementia. aug: au: Pal, Anita Behari, Madhuri Sharma, Ratna affil: Department of Physiology, All India Institute of Medical Sciences, New Delhi, India sug: subj: Parkinson Disease Diagnosis Dementia Diagnosis Comorbidity Electroencephalography Methods Memory, Short Term Task Performance and Analysis Brain Waves Human Funding Source Dementia Symptoms Diagnosis, Differential Image Processing, Computer Assisted Cognition Severity of Illness Evaluation Biological Markers Psychological Tests ab: Background and Objectives: Working memory (WM) impairment is a common and progressive abnormality in Parkinson's disease (PD), which ultimately leads to dementia. Individuals with PD exhibit altered electroencephalogram (EEG) patterns while engaging in tasks that require WM. The study examined the EEG patterns associated with WM maintenance in PD patients. Methods: The study consisted of two groups of PD patients with a sign of dementia (PDD) who had a Mini Mental State Examination (MMSE) score ≤24, PD patients with no sign of dementia (PDND) with an MMSE score >24, and a group of healthy individuals serving as controls (CON). We obtained EEG during a word memorization task using a 128-channel system. The spectral power of the EEG was computed using the fast Fourier transformation algorithm. Results: Compared to both PDND and CON groups, PDD group exhibited higher power in the delta and beta frequency bands. Conversely, there was a notable decrease in power in the gamma band in both the PDD and PDND groups compared to the CON group. In addition, the PDD group exhibited higher power in the gamma band compared to the PDND group. Power in the alpha (LA1, LA2, and UA) and theta bands was greater in PDND and PDD compared to CON, but was similar between PDND and PDD groups. Conclusion: While performing WM tasks, PDD exhibits increased delta and beta power. These findings can be used as a quantitative biomarker to evaluate the severity of initial WM impairments, which could potentially develop into dementia in the future. pubtype: Academic Journal doctype: diagnostic images research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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