Navigating the microbial maze: unraveling the connection between gut microbiome and pediatric kidney and urinary tract disease.
The gut microbiome is made up of trillions of bacteria, viruses, archaea, and microbes that play a significant role in the maintenance of normal physiology in humans. Recent research has highlighted the effects of the microbiome and its dysbiosis in the pathogenesis and maintenance of kidney disease...
| Publicado en: | Pediatric Nephrology Vol. 40; no. 2; pp. 339 - 354 |
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| Autores principales: | , , , , |
| Formato: | pictorial review tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181827922&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181827922 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0931041X EF1 jtl: Pediatric Nephrology issn: 0931041X maglogo: N pubinfo: dt: Feb2025 vid: 40 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 181827922 177622458 181827922 181827922 10.1007/s00467-024-06357-x 181827922 ppf: 339 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Navigating the microbial maze: unraveling the connection between gut microbiome and pediatric kidney and urinary tract disease. aug: au: Kusumi, Kirsten Islam, Muhammad S. Banker, Himanshi Safadi, Fayez F. Raina, Rupesh affil: https://ror.org/003rfsp33 Pediatric Nephrology and Hypertension, Nationwide Children's Hospital, Columbus, OH, USA sug: subj: Urinary Tract Infections Diagnosis Kidney Diseases Diagnosis Gut Microbiota Bone Density Child Development Kidney Calculi Nephrotic Syndrome Pathologic Processes Immunoglobulins Child Adolescence Research, Medical Diet Probiotics Therapeutic Use Preventive Health Care Morbidity Prevention and Control Urinary Tract Infections Drug Therapy Kidney Diseases Drug Therapy Mortality Prevention and Control Kidney Diseases Mortality Urinary Tract Infections Mortality Child: 6-12 years Adolescent: 13-18 years ab: The gut microbiome is made up of trillions of bacteria, viruses, archaea, and microbes that play a significant role in the maintenance of normal physiology in humans. Recent research has highlighted the effects of the microbiome and its dysbiosis in the pathogenesis and maintenance of kidney disease, especially chronic kidney disease (CKD) and its associated cardiovascular disease. While studies have addressed the kidney-microbiome axis in adults, how dysbiosis may uniquely impact pediatric kidney disease patients is not well-established. This narrative review highlights all relevant studies focusing on the microbiome and pediatric kidney disease that were published between 7/2015 and 7/2023. This review highlights pediatric-specific considerations including growth and bone health as well as emphasizing the need for increased pediatric research. Understanding microbiome-kidney interactions may allow for novel, less invasive interventions such as dietary changes and the use of probiotics to improve preventive care and ameliorate long-term morbidity and mortality in this vulnerable population. pubtype: Academic Journal doctype: pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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