Tubulointerstitial nephritis in children and adolescents.
The tubulointerstitial compartment comprises most of the kidney parenchyma. Inflammation in this compartment (tubulointerstitial nephritis—TIN) can be acute and resolves if the offending factor is withdrawn or may enter a chronic process leading to irreversible kidney damage. Etiologic factors diffe...
| Publicado en: | Pediatric Nephrology Vol. 40; no. 2; pp. 319 - 329 |
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| Autores principales: | , |
| Formato: | algorithm pictorial review tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181827948&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181827948 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0931041X EF1 jtl: Pediatric Nephrology issn: 0931041X maglogo: N pubinfo: dt: Feb2025 vid: 40 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 181827948 179868276 181827948 181827948 10.1007/s00467-024-06526-y 181827948 ppf: 319 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Tubulointerstitial nephritis in children and adolescents. aug: au: Gurevich, Evgenia Landau, Daniel affil: Pediatrics Department, Barzilai University Medical Center, Ashqelon, Israel sug: subj: Nephritis, Interstitial Physiopathology Nephritis, Interstitial Physiopathology Chronic Disease Necroptosis Fibrosis Renal Insufficiency, Chronic Nephritis, Interstitial Etiology Nephritis, Interstitial Immunology Nephritis, Interstitial Familial and Genetic Nephritis, Interstitial Complications Nephritis, Interstitial Symptoms Disease Attributes Nephritis, Interstitial Diagnosis Nephritis, Interstitial Therapy Adolescence Child Adolescent: 13-18 years Child: 6-12 years ab: The tubulointerstitial compartment comprises most of the kidney parenchyma. Inflammation in this compartment (tubulointerstitial nephritis—TIN) can be acute and resolves if the offending factor is withdrawn or may enter a chronic process leading to irreversible kidney damage. Etiologic factors differ, including different exposures, infections, and autoimmune and genetic tendency, and the initial damage can be acute, recurrent, or permanent, determining whether the acute inflammatory process will lead to complete healing or to a chronic course of inflammation leading to fibrosis. Clinical and laboratory findings of TIN are often nonspecific, which may lead to delayed diagnosis and a poorer clinical outcome. We provide a general review of TIN, with special mention of the molecular pathophysiological mechanisms of the associated kidney damage. pubtype: Academic Journal doctype: algorithm pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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