Feature Extraction and Identification of Rheumatoid Nodules Using Advanced Image Processing Techniques.

Background/Objectives: Accurate detection and classification of nodules in medical images, particularly rheumatoid nodules, are critical due to the varying nature of these nodules, where their specific type is often unknown before analysis. This study addresses the challenges of multi-class predicti...

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Published in:Rheumato Vol. 4; no. 4; pp. 176 - 193
Main Authors: Mubeen, Azmath, Dulhare, Uma N.
Format: diagnostic images equations & formulas research tables/charts Journal Article
Published: MDPI Dec2024
Online Access:View this record in EBSCOhost
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      dt: Dec2024
      vid: 4
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      pid: 97109
      pub: MDPI
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        181939050
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        10.3390/rheumato4040014
        181939050
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        atl: Feature Extraction and Identification of Rheumatoid Nodules Using Advanced Image Processing Techniques.
      aug:
        au:
          Mubeen, Azmath
          Dulhare, Uma N.
        affil: Department of Computer Science, University College for Women, Koti, Hyderabad 500095, India
      sug:
        subj:
          Rheumatoid Nodule Diagnosis
          Rheumatoid Nodule Classification
          Image Processing, Computer Assisted Methods
          Diagnostic Imaging Methods
          Diagnosis, Computer Assisted
          Sensitivity and Specificity
          Quality Improvement
          Human
          Diagnosis, Differential
          Rheumatoid Nodule Symptoms
          Rheumatoid Nodule Pathology
          Convolutional Neural Networks Evaluation
          Particle Swarm Optimization
          Precision
          Prediction Algorithms
          Detection Algorithms
      ab: Background/Objectives: Accurate detection and classification of nodules in medical images, particularly rheumatoid nodules, are critical due to the varying nature of these nodules, where their specific type is often unknown before analysis. This study addresses the challenges of multi-class prediction in nodule detection, with a specific focus on rheumatoid nodules, by employing a comprehensive approach to feature extraction and classification. We utilized a diverse dataset of nodules, including rheumatoid nodules sourced from the DermNet dataset and local rheumatologists. Method: This study integrates 62 features, combining traditional image characteristics with advanced graph-based features derived from a superpixel graph constructed through Delaunay triangulation. The key steps include image preprocessing with anisotropic diffusion and Retinex enhancement, superpixel segmentation using SLIC, and graph-based feature extraction. Texture analysis was performed using Gray-Level Co-occurrence Matrix (GLCM) metrics, while shape analysis was conducted with Fourier descriptors. Vascular pattern recognition, crucial for identifying rheumatoid nodules, was enhanced using the Frangi filter. A Hybrid CNN–Transformer model was employed for feature fusion, and feature selection and hyperparameter tuning were optimized using Gray Wolf Optimization (GWO) and Particle Swarm Optimization (PSO). Feature importance was assessed using SHAP values. Results: The proposed methodology achieved an accuracy of 85%, with a precision of 0.85, a recall of 0.89, and an F1 measure of 0.87, demonstrating the effectiveness of the approach in detecting and classifying rheumatoid nodules in both binary and multi-class classification scenarios. Conclusions: This study presents a robust tool for the detection and classification of nodules, particularly rheumatoid nodules, in medical imaging, offering significant potential for improving diagnostic accuracy and aiding in the early identification of rheumatoid conditions.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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