Investigating the Feasibility of Gap Prepulse Inhibition by Auditory Middle Latency Responses in Healthy Subjects.
Background and Aim: Gap Prepulse Inhibition (GPI) is a type of Prepulse Inhibition (PPI) in which a gap is used as a prepulse. This study was conducted to investigate the silence gap effect on Auditory Middle Latency Response (AMLR) inhibition in normal subjects. Methods: In this study, 25 participa...
| Publicado en: | Auditory & Vestibular Research (2423-480X) Vol. 33; no. 4; pp. 330 - 339 |
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| Autores principales: | , , |
| Formato: | research tables/charts tracings Journal Article |
| Publicado: |
Tehran University of Medical Sciences
2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=181999702&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 181999702 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2423480X MB4D jtl: Auditory & Vestibular Research (2423-480X) issn: 2423480X maglogo: N pubinfo: dt: 2024 vid: 33 iid: 4 pid: 21783 pub: Tehran University of Medical Sciences artinfo: ui: 181999702 181999702 181999702 10.18502/avr.v33i4.16651 181999702 ppf: 330 ppct: 9 formats: tig: atl: Investigating the Feasibility of Gap Prepulse Inhibition by Auditory Middle Latency Responses in Healthy Subjects. aug: au: Seraji, Hossein Mohammadkhani, Ghassem Afzalzadeh, Mohamad Reza affil: Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran sug: subj: Nervous System Physiology Acoustic Stimulation Hearing Human Iran Male Female Adult Descriptive Statistics Paradigms Tinnitus Diagnosis Paired T-Tests Data Analysis Software Adult: 19-44 years Male Female ab: Background and Aim: Gap Prepulse Inhibition (GPI) is a type of Prepulse Inhibition (PPI) in which a gap is used as a prepulse. This study was conducted to investigate the silence gap effect on Auditory Middle Latency Response (AMLR) inhibition in normal subjects. Methods: In this study, 25 participants with normal hearing and no history of tinnitus were included. AMLR was recorded in response to stimuli with gap and without gap in two background noises of 2 and 8 kHz at two electrode locations Fz and Cz and then, gap prepulse inhibition for Na-Pa, Pa-Nb, Nb-Pb and Pb-Nc amplitude with Use of responses to stimuli with and without gap was calculated. Results: The results showed that the mean amplitudes of all four AMLR indices decreased in response to the stimuli with gap and this decrease was more and statistically significant in 8 kHz background noise (p=0.001). Conclusion: According to the results of this study, it seems that in future studies, PPI of Na-Pa and Pb-Nc amplitudes can be used as main indicators and PPI of Pa-Nb and Nb-Pb amplitudes as alternative indicators in the PPI paradigm in tinnitus diagnosis. pubtype: Academic Journal doctype: research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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