Autoinflammatory Bone Diseases.
Autoinflammatory bone diseases (AIBDs) constitute a recently identified subset of autoinflammatory diseases. These conditions are characterized by an exaggerated inflammatory response in the bones without any apparent etiology. Inflammatory bone lesions associated with AIBDs exhibit chronic inflamma...
| Publicado en: | Balkan Medical Journal Vol. 42; no. 1; pp. 5 - 14 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images pictorial review tables/charts Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Jan2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182029542&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182029542 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 21463123 BM3Q jtl: Balkan Medical Journal issn: 21463123 maglogo: N pubinfo: dt: Jan2025 vid: 42 iid: 1 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 182029542 182029542 182029542 10.4274/balkanmedj.galenos.2024.2024-11-129 182029542 ppf: 5 ppct: 9 formats: tig: atl: Autoinflammatory Bone Diseases. aug: au: Haşlak, Fatih Akay, Nergis Gül, Ümit Günalp, Aybüke Könte, Elif Kılıç Şahin, Sezgin Kasapçopur, Özgür affil: Department of Pediatric Rheumatology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye sug: subj: Bone Diseases Hereditary Autoinflammatory Diseases Genetics, Medical Genetic Research Musculoskeletal Diseases Complications Genetic Screening Bone Diseases Symptoms Bone Diseases Diagnosis Bone Diseases Familial and Genetic Bone Diseases Etiology Bone Diseases Therapy Bone Diseases Pathology Hereditary Autoinflammatory Diseases Symptoms Hereditary Autoinflammatory Diseases Diagnosis Hereditary Autoinflammatory Diseases Familial and Genetic Hereditary Autoinflammatory Diseases Etiology Hereditary Autoinflammatory Diseases Therapy Hereditary Autoinflammatory Diseases Pathology ab: Autoinflammatory bone diseases (AIBDs) constitute a recently identified subset of autoinflammatory diseases. These conditions are characterized by an exaggerated inflammatory response in the bones without any apparent etiology. Inflammatory bone lesions associated with AIBDs exhibit chronic inflammation, are typically culture-negative, and do not exhibit discernible microorganisms on histopathological examination. The most common and representative AIBD is chronic non-bacterial osteomyelitis (CNO), which is also known as chronic recurrent multifocal osteomyelitis. Another variant of CNO, which is typically observed in older teenagers or adults, is known as synovitis, acne, hyperostosis, pustulosis, osteitis syndrome. This condition is distinguished by its notable skin manifestations. Advancements in genetic research have led to the identification of three novel monogenic subtypes within the category of AIBDs. These include Majeed syndrome, pyogenic arthritis, pyoderma gangrenosum, and acne syndrome, and interleukin-1 receptor antagonist deficiency syndrome. Another monogenic AIBD, called cherubism, affects only the maxilla and mandible. Data on the diagnosis and treatment of these rare diseases are extremely limited. However, if not diagnosed and treated promptly, it can result in significant complications, including severe disability and mortality. Thus, it is imperative to maintain a high level of clinical awareness of these diseases. These rare diagnoses should be considered in patients with musculoskeletal complaints in whom no specific etiology can be identified or in patients with systemic manifestations such as cutaneous and gastrointestinal symptoms or fever. In such patients, the diagnostic process, which encompasses imaging and genetic studies, should be initiated promptly. pubtype: Academic Journal doctype: diagnostic images pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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