Influence of Micro- and Nanoplastics on Mitochondrial Function in the Cardiovascular System: A Review of the Current Literature.

Mitochondria represent pivotal cellular organelles endowed with multifaceted functionalities encompassing cellular respiration, metabolic processes, calcium turnover, and the regulation of apoptosis, primarily through the generation of reactive oxygen species (ROS). Perturbations in mitochondrial dy...

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Publicado en:Physiological Research Vol. 73; pp. 685 - 696
Autores principales: LERCHNER, Tobias, JEDLIČKA, Jan, KRIPNEROVÁ, Michaela, DEJMEK, Jiří, KUNCOVÁ, Jitka
Formato: Journal Article
Publicado: Institute of Physiology, Academy of Sciences of the Czech Republic 2024 Supplement
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Influence of Micro- and Nanoplastics on Mitochondrial Function in the Cardiovascular System: A Review of the Current Literature.
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          LERCHNER, Tobias
          JEDLIČKA, Jan
          KRIPNEROVÁ, Michaela
          DEJMEK, Jiří
          KUNCOVÁ, Jitka
        affil: Institute of Physiology, Faculty of Medicine in Plzen, Charles University, Czech Republic
      sug:
      ab: Mitochondria represent pivotal cellular organelles endowed with multifaceted functionalities encompassing cellular respiration, metabolic processes, calcium turnover, and the regulation of apoptosis, primarily through the generation of reactive oxygen species (ROS). Perturbations in mitochondrial dynamics have been intricately linked to the etiology of numerous cardiovascular pathologies, such as heart failure, ischemic heart disease, and various cardiomyopathies. Notably, recent attention has been directed towards the detrimental impact of micro- and nanoplastic pollution on mitochondrial integrity, an area underscored by a paucity of comprehensive investigations. Given the escalating prevalence of plastic particle contamination and the concomitant burden of cardiovascular disease in aging populations, understanding the interplay between mitochondria within the cardiovascular system and micro- and nanoplastic pollution assumes paramount importance. This review endeavors to elucidate the current albeit limited comprehension surrounding this complex interplay.
      pubtype: Academic Journal
      doctype: Journal Article
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    language: English
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