MRI features of combined hepatocellular-cholangiocarcinoma.
Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a rare liver tumor which has a more aggressive behavior and worse survival outcome than hepatocellular carcinoma (HCC), with a prognosis similar to that of intrahepatic cholangiocarcinoma (iCCA). With limited literature on the appearance of th...
| Publicado en: | Abdominal Radiology Vol. 50; no. 1; pp. 169 - 185 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jan2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182152180&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182152180 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Jan2025 vid: 50 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 182152180 10.1007/s00261-024-04476-5 182152180 ppf: 169 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: MRI features of combined hepatocellular-cholangiocarcinoma. aug: au: Majeed, Noor Fatima Macey, Mathew Amirfarzan, Marta Braschi Sharifi, Sheida Wortman, Jeremy R affil: https://ror.org/03czfpz43 Department of Radiology, Emory University School of Medicine, Atlanta, GA, USA sug: ab: Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a rare liver tumor which has a more aggressive behavior and worse survival outcome than hepatocellular carcinoma (HCC), with a prognosis similar to that of intrahepatic cholangiocarcinoma (iCCA). With limited literature on the appearance of this tumor on MRI, it remains a diagnostic challenge. In this review, we looked at the currently described MRI findings in this uncommon entity. Based on studies conducted to date, a mixed pattern at imaging has demonstrated the highest specificity, seen as a combination of areas showing progressive enhancement of the lesion, arterial enhancement with washout, and areas of arterial enhancement without washout and/or hypovascularity. Tumor markers may aid in identification, particularly in cases where the imaging appearance mimics that of isolated HCC or iCCA. Intratumoral heterogeneity leads to difficulties with pathologic diagnosis from sampling due to the possibility of an incorrect diagnosis if the biopsy specimen does not contain adequate tissue comprising both histologic components. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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