Pharmacotherapeutic actions related to drug interaction alerts – a questionnaire study among Swedish hospital interns and residents in family medicine.
Purpose: To explore how hospital interns and residents specialising in family medicine act on drug interaction alerts in a specific patient case, and on interaction alerts in general. Methods: A 4-page questionnaire, including a fictional patient case (73-year-old woman; 10 drugs in the medication l...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 81; no. 2; pp. 301 - 309 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182154265&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182154265 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00316970 NP9 jtl: European Journal of Clinical Pharmacology issn: 00316970 maglogo: N pubinfo: dt: Feb2025 vid: 81 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 182154265 181675989 182154265 182154265 10.1007/s00228-024-03785-4 182154265 ppf: 301 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Pharmacotherapeutic actions related to drug interaction alerts – a questionnaire study among Swedish hospital interns and residents in family medicine. aug: au: Tukukino, Carina Parodi López, Naldy Lönnbro, Johan Wallerstedt, Susanna M. Svensson, Staffan A. affil: https://ror.org/01tm6cn81 Department of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden sug: subj: Drug Interactions Interns and Residents Academic Medical Centers Primary Health Care Physicians Decision Support Systems, Clinical Electronic Order Entry Human Swedes Sweden Aged Questionnaires Repaglinide Clopidogrel Bisulfate Omeprazole Citalopram Thyroxine Funding Source Medication Errors Prevention and Control Male Female Adult Aged: 65+ years Adult: 19-44 years Male Female ab: Purpose: To explore how hospital interns and residents specialising in family medicine act on drug interaction alerts in a specific patient case, and on interaction alerts in general. Methods: A 4-page questionnaire, including a fictional patient case (73-year-old woman; 10 drugs in the medication list triggering 11 drug interaction alerts) and questions regarding the use of interaction alerts in general, was distributed to interns and residents during educational sessions (November‒December 2023). The respondents were instructed to consider what actions they would take "a normal day at work" due to the risk of interactions between the patients' drugs. In the general questions, the respondents were asked how often they access the detailed interaction information (from 1 = never to 5 = always) provided by the knowledge resource, in relation to the alert classification (D = clinically significant, should be avoided; C = clinically significant, can be handled by, e.g., dose adjustment). Results: The questionnaire was completed by 55 interns and 69 residents (response rate: 98%). In the patient case, the respondents acted on a median of 4 (range: 0‒8) drugs, most often concerning repaglinide (in a D interaction alert with clopidogrel; 96% of the interns and 96% of the residents suggested action), and omeprazole (in three C interaction alerts with citalopram, clopidogrel, and levothyroxine, respectively; 71% and 83% suggested action). Among the respondents who answered the questions about how often (rated 4/5) they access more detailed information about interactions, 56 (59%) did so for D versus 29 (31%) for C alerts (P < 0.001). Conclusion: Physicians act on drug interaction alerts selectively, and the alert classifications seem to guide how they are used. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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