Classification of Patients Based on Dyspnea and Desaturation During Exercise in Interstitial Lung Disease.

Background: Dyspnea and desaturation during exercise are essential assessment items for pulmonary rehabilitation. Characterizing patients using these 2 factors may be important for providing more effective pulmonary rehabilitation. This study aimed to categorize subjects with interstitial lung disea...

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Publicado en:Respiratory Care Vol. 70; no. 1; pp. 56 - 65
Autores principales: Otake, Kohei, Misu, Shogo, Yamamoto, Akio, Yamaguchi, Takumi, Nagatani, Chisato, Sakai, Hideki, Kaneko, Masahiro, Ishikawa, Akira, Tomioka, Hiromi
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Jan2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2025
      vid: 70
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      pub: Mary Ann Liebert, Inc.
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        10.1089/respcare.11712
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        atl: Classification of Patients Based on Dyspnea and Desaturation During Exercise in Interstitial Lung Disease.
      aug:
        au:
          Otake, Kohei
          Misu, Shogo
          Yamamoto, Akio
          Yamaguchi, Takumi
          Nagatani, Chisato
          Sakai, Hideki
          Kaneko, Masahiro
          Ishikawa, Akira
          Tomioka, Hiromi
        affil: Mr. Otake is affiliated with Department of Physical Therapy, Faculty of Nursing and Rehabilitation, Chubu Gakuin University, Seki City, Japan.
      sug:
        subj:
          Lung Diseases, Interstitial Physiopathology
          Dyspnea Physiopathology
          Oxygen Saturation
          Exercise Test
          Respiratory Function Tests
          Human
          Male
          Female
          Retrospective Design
          Record Review
          Japan
          Pulse Oximeters
          Descriptive Statistics
          Clinical Assessment Tools
          Cluster Analysis
          Mann-Whitney U Test
          Unpaired T-Tests
          Pearson's Correlation Coefficient
          Chi Square Test
          Analysis of Variance
          Kruskal-Wallis Test
          Exercise Tolerance
          Middle Age
          Aged
          Aged, 80 and Over
          Scales
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: Dyspnea and desaturation during exercise are essential assessment items for pulmonary rehabilitation. Characterizing patients using these 2 factors may be important for providing more effective pulmonary rehabilitation. This study aimed to categorize subjects with interstitial lung disease (ILD) using dyspnea and desaturation at the end of the 6-min walk test (6MWT). Methods: This was a retrospective study including 230 stable subjects with ILD who underwent 6MWT in our out-patient department at a general hospital in Japan. The modified Borg scale and oxygen saturation determined by SpO2 at the end of the 6MWT were used for cluster analysis using the k-means method with k = 4. Results: Subjects were classified into 4 characteristic clusters. SpO2 at the end of the 6MWT was lower in cluster 4 (80.5 ± 3.0%) than in clusters 1 (94.3 ± 2.0%), 2 (94.3 ± 1.9%), and 3 (87.9 ± 1.8%) and was lower in cluster 3 than in clusters 1 and 2. The modified Borg scale score at the end of the 6MWT was higher in clusters 2 (4 [3–8]), 3 (3 [0–9]), and 4 (4 [0–7]) than in cluster 1 (0.5 [0–2.0]) and was higher in cluster 2 than in cluster 3. Conclusions: Subjects with ILD were classified into 4 characteristic clusters using dyspnea and SpO2 at the end of the 6MWT. The 4 clusters are characterized as follows: Cluster 1 had mild desaturation and mild dyspnea; cluster 2 had mild desaturation and severe dyspnea; cluster 3 had both moderate desaturation and dyspnea, and cluster 4 had both severe desaturation and dyspnea. These classification data offer insight for individualized pulmonary rehabilitation for patients with ILD.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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