The Electronic Properties and Reactivity of 4 (4-Substituted phenyl) -1,2,5- Selenadiazole Derivatives.

This study presents a theoretical investigation of 4-(4- substituted phenyl) -1,2,5- selenadiazole derivatives, focusing on the impact of para-substituents on their electronic properties and reactivity. Semi-empirical PM3 and density functional theory (DFT) methods (B3LYP/3- 21G) were employed for m...

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Publicado en:Journal of Basrah Researches (Sciences) Vol. 50; no. 2; pp. 257 - 266
Autores principales: Hameed, Ali Jameel, Azad, Seta
Formato: Artículo
Publicado: Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR) 2024
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Acceso en línea:Ver este registro en EBSCOhost
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      pub: Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR)
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        atl: The Electronic Properties and Reactivity of 4 (4-Substituted phenyl) -1,2,5- Selenadiazole Derivatives.
      aug:
        au:
          Hameed, Ali Jameel
          Azad, Seta
        affil:
          Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq.
          Department of Pharmaceutical Chemistry, College of Pharmacy, University of Basrah, Basrah, Iraq.
      su:
        Proton affinity
        Chemical kinetics
        Molecular shapes
        Band gaps
        Materials science
      sug:
        subj:
          Proton affinity
          Chemical kinetics
          Molecular shapes
          Band gaps
          Materials science
      keyword:
        1,2,5-Selenadiazole
        DFT theory
        Proton Affinity
        Reactivity Indices
        مؤشرات التفاعل
        نظرية DFT
        1,2,5 - سيلينا ديازول، تقارب البروتون
      ab: This study presents a theoretical investigation of 4-(4- substituted phenyl) -1,2,5- selenadiazole derivatives, focusing on the impact of para-substituents on their electronic properties and reactivity. Semi-empirical PM3 and density functional theory (DFT) methods (B3LYP/3- 21G) were employed for molecular geometry optimization and electronic structure analysis. Key findings include significant substituent effects on HOMO-LUMO energy gaps, proton affinities, and reactivity indices. Electron-donating groups, particularly NMe2, notably enhanced molecular softness and reduced energy gaps, indicating increased chemical reactivity. Proton affinity calculations revealed systematic trends for electron-donating groups, while electron-withdrawing groups showed less consistent behavior. These insights provide a foundation for the potential application of these derivatives in catalysis, materials science, and drug development, highlighting the utility of computational methods in predicting structure-property relationships.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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          year: 2024
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