A critical review on approaches to generate and validate virtual population for physiologically based pharmacokinetic models: Methodologies, case studies and way forward.
Purpose: In silico modeling and simulation techniques such as physiologically based pharmacokinetic (PBPK) and physiologically based biopharmaceutics modeling (PBBM) have demonstrated various applications in drug discovery and development. Virtual bioequivalence leverages these computation tools to...
| Published in: | European Journal of Clinical Pharmacology Vol. 80; no. 12; pp. 1903 - 1923 |
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| Main Authors: | , , , |
| Format: | equations & formulas review tables/charts Journal Article |
| Published: |
Springer Nature
Dec2024
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| Online Access: | View this record in EBSCOhost |