RDLR: A Robust Deep Learning-Based Image Registration Method for Pediatric Retinal Images.

Retinal diseases stand as a primary cause of childhood blindness. Analyzing the progression of these diseases requires close attention to lesion morphology and spatial information. Standard image registration methods fail to accurately reconstruct pediatric fundus images containing significant disto...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 6; pp. 3131 - 3146
Autores principales: Zhou, Hao, Yang, Wenhan, Sun, Limei, Huang, Li, Li, Songshan, Luo, Xiaoling, Jin, Yili, Sun, Wei, Yan, Wenjia, Li, Jing, Ding, Xiaoyan, He, Yao, Xie, Zhi
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Dec2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2024
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      pub: Springer Nature
      place: New York, New York
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        atl: RDLR: A Robust Deep Learning-Based Image Registration Method for Pediatric Retinal Images.
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        au:
          Zhou, Hao
          Yang, Wenhan
          Sun, Limei
          Huang, Li
          Li, Songshan
          Luo, Xiaoling
          Jin, Yili
          Sun, Wei
          Yan, Wenjia
          Li, Jing
          Ding, Xiaoyan
          He, Yao
          Xie, Zhi
        affil: State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China
      sug:
        subj:
          Retinal Diseases Radiography
          Retinal Diseases Pathology
          Image Interpretation, Computer Assisted Methods
          Image Processing, Computer Assisted Methods
          Deep Learning
          Human
          Male
          Female
          Child
          Child, Preschool
          Infant
          Quality Control (Technology)
          Reliability
          Child: 6-12 years
          Child, Preschool: 2-5 years
          Infant: 1-23 months
          Male
          Female
      ab: Retinal diseases stand as a primary cause of childhood blindness. Analyzing the progression of these diseases requires close attention to lesion morphology and spatial information. Standard image registration methods fail to accurately reconstruct pediatric fundus images containing significant distortion and blurring. To address this challenge, we proposed a robust deep learning–based image registration method (RDLR). The method consisted of two modules: registration module (RM) and panoramic view module (PVM). RM effectively integrated global and local feature information and learned prior information related to the orientation of images. PVM was capable of reconstructing spatial information in panoramic images. Furthermore, as the registration model was trained on over 280,000 pediatric fundus images, we introduced a registration annotation automatic generation process coupled with a quality control module to ensure the reliability of training data. We compared the performance of RDLR to the other methods, including conventional registration pipeline (CRP), voxel morph (WM), generalizable image matcher (GIM), and self-supervised techniques (SS). RDLR achieved significantly higher registration accuracy (average Dice score of 0.948) than the other methods (ranging from 0.491 to 0.802). The resulting panoramic retinal maps reconstructed by RDLR also demonstrated substantially higher fidelity (average Dice score of 0.960) compared to the other methods (ranging from 0.720 to 0.783). Overall, the proposed method addressed key challenges in pediatric retinal imaging, providing an effective solution to enhance disease diagnosis. Our source code is available at https://github.com/wuwusky/RobustDeepLeraningRegistration.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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