Modifiable Risk Factors Including Self-Perceived Stress for Breast Cancer in Hong Kong: A Case-Control Study of 10 757 Subject.

Background: In Hong Kong, breast cancer is the commonest female cancer. In addition to intrinsic risk factors that cannot be modified, other factors may be potentially modifiable. The objective of this report was to determine modifiable risk factors in association with breast cancer among Chinese wo...

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Publicado en:Clinical Medicine Insights: Oncology pp. 1 - 10
Autores principales: Yeo, Winnie, Yuen, Lok-Wa, Tsoi, Kelvin Kam-Fai, Chan, Emily Ying-Yang, Kwok, Carol C, Soong, Inda, Ng, Ting-Ying, Chiu, Joanne, Chan, Miranda, Chan, Sharon Wing-Wai, Wong, Ting-Ting, Chan, Yolanda Ho-Yan, Li, Lawrence Pui-Ki, Yau, Chun-Chung, Hung, Wai-Ka, Cheung, Polly Suk-Yee
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. 1/24/2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 1/24/2025
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        atl: Modifiable Risk Factors Including Self-Perceived Stress for Breast Cancer in Hong Kong: A Case-Control Study of 10 757 Subject.
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        au:
          Yeo, Winnie
          Yuen, Lok-Wa
          Tsoi, Kelvin Kam-Fai
          Chan, Emily Ying-Yang
          Kwok, Carol C
          Soong, Inda
          Ng, Ting-Ying
          Chiu, Joanne
          Chan, Miranda
          Chan, Sharon Wing-Wai
          Wong, Ting-Ting
          Chan, Yolanda Ho-Yan
          Li, Lawrence Pui-Ki
          Yau, Chun-Chung
          Hung, Wai-Ka
          Cheung, Polly Suk-Yee
        affil: Department of Clinical Oncology, Prince of Wales Hospital, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong
      sug:
        subj:
          Breast Neoplasms Risk Factors
          Stress, Psychological Complications
          Risk Assessment
          Chinese Persons Psychosocial Factors
          Women
          Human
          Hong Kong
          Female
          Male
          Case Control Studies
          Cancer Patients
          Control Group
          Diet
          Exercise
          Contraceptives, Oral
          Obesity
          Parity
          Questionnaires
          Interviews
          Summated Rating Scaling
          Chi Square Test
          One-Way Analysis of Variance
          Odds Ratio
          Confidence Intervals
          Data Analysis Software
          Descriptive Statistics
          Female
          Male
      ab: Background: In Hong Kong, breast cancer is the commonest female cancer. In addition to intrinsic risk factors that cannot be modified, other factors may be potentially modifiable. The objective of this report was to determine modifiable risk factors in association with breast cancer among Chinese women in our locality. Methods: This is a case-control study that enrolled breast cancer patients from the Hong Kong Breast Cancer Registry and healthy matched controls from the local community between 2014 and 2017. Potential risk factors were analyzed using multiple logistic regression. Results: In total, 5186 breast cancer patients and 5571 controls were recruited. Several modifiable risk factors were identified. Self-perceived high stress level (adjusted odd ratios [AOR]= 3.44; 95% confidence intervals [CI] = 3.13-3.78), dairy-rich diet (AOR = 3.33; 95% CI = 2.01-5.52), delayed child-bearing (AOR = 2.23; 95% CI = 1.79-2.79), meat-rich diet (AOR = 1.77; 95% CI = 1.54-2.04), ever use of oral contraceptives (AOR = 1.34; 95% CI = 1.22-1.47), nulliparity (AOR = 1.21; 95% CI = 1.08-1.35), and being overweight/obese (AOR = 1.21; 95% CI = 1.10-1.32) were found to be associated with an increased risk of breast cancer. On the other hand, breastfeeding (AOR = 0.76; 95% CI = 0.69-0.83) and exercise (odds ratio = 0.62; 95% CI = 0.56-0.68) were associated with decreased risk. Conclusions: In our locality, high-stress level, meat- and dairy-rich diet, reproductive history, use of oral contraceptives, and being overweight/obese were identified to be modifiable risk factors for breast cancer. Lifestyle modification may help reduce breast cancer incidence in the coming decades.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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