Electroencephalography Correlation of Ketamine-induced Clinical Excitatory Movements: A Systematic Review.
Background: This is a systematic review investigating the correlation between seizures identifiable on electroencephalogram (EEG), clinical excitatory movements (CEM), and ketamine administration for procedural sedation. Methods: We searched MEDLINE, EMBASE, Cochrane CENTRAL, and Web of Science in A...
| Publicado en: | Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health Vol. 26; no. 1; pp. 147 - 155 |
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| Autores principales: | , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health
Jan2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182494390&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182494390 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1936900X 8B61 jtl: Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health issn: 1936900X maglogo: N pubinfo: dt: Jan2025 vid: 26 iid: 1 pid: 29816 pub: Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health place: Orange, California artinfo: ui: 182494390 182494390 182494390 10.5811/westjem.18611 182494390 ppf: 147 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Electroencephalography Correlation of Ketamine-induced Clinical Excitatory Movements: A Systematic Review. aug: au: Tunc, Emine M. Uspal, Neil Morgan, Lindsey Groshong, Sue L. Brown, Julie C. affil: University of Texas Southwestern, Department of Pediatrics, Division of Emergency Medicine, Dallas, Texas sug: subj: Seizures Etiology Electroencephalography Ketamine Administration and Dosage Ketamine Adverse Effects Epilepsy Diagnosis Epilepsy Drug Therapy Outcome Assessment Evaluation Human Male Female Adult Child Systematic Review Sedation Medline Embase Cochrane Library Status Epilepticus Muscle Spasticity Myoclonus Adult: 19-44 years Child: 6-12 years Male Female ab: Background: This is a systematic review investigating the correlation between seizures identifiable on electroencephalogram (EEG), clinical excitatory movements (CEM), and ketamine administration for procedural sedation. Methods: We searched MEDLINE, EMBASE, Cochrane CENTRAL, and Web of Science in April 2021. Search terms included variations for ketamine, myoclonus, seizures, status epilepticus, and electroencephalography. Two independent reviewers assessed papers based on eligibility criteria, which included human studies where EEG recordings were obtained during ketamine administration. Results: Eight papers were eligible for inclusion with 141 subjects (24 children). Seven studies (133 subjects) reported epilepsy history; 70% (94/133) of these subjects had a pre-existing epilepsy diagnosis. No (0/39) subjects without epilepsy and 28% (26/94) of subjects with epilepsy had electrographic seizures after ketamine administration. In four studies where pediatric and adult subjects could be separated, children with epilepsy had electrographic seizures in 60% (3/5) of cases compared to 28% (6/33) of cases of adults with epilepsy. Of the subjects with epilepsy, 14% (10/74) had CEMs vs 5% (1/21) in subjects without epilepsy. Most CEMs (9/11) were temporally correlated with electrographic seizures. Conclusions: Our findings indicate that in subjects with epilepsy, electrographic seizures were frequently seen with ketamine administration and were correlated with CEMs. No seizure activity after ketamine was seen in subjects without epilepsy. While the clinical significance of these findings needs further investigation, clinicians may want to consider patients' seizure history when providing counseling on the risks and benefits of ketamine sedation. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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